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Dpp10 Gene Detail
Summary
  • Symbol
    Dpp10
  • Name
    dipeptidylpeptidase 10
  • Synonyms
    6430601K09Rik, DPRP3
  • Feature Type
    protein coding gene
  • IDs
    MGI:2442409
    NCBI Gene: 269109
  • Gene Overview
    MyGene.info: DPP10
Location & Maps
more
  • Sequence Map
    Chr1:123321471-124045559 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser
  • Download
    Sequence
      724089 bp   ±  kb flank

  • Genome Browsers
    VEGA | Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 53.68 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    DPP10, dipeptidyl peptidase like 10
  • Vertebrate Orthologs
    11
  • Human Ortholog
    DPP10, dipeptidyl peptidase like 10
    Orthology source: HomoloGene, HGNC
  • Synonyms
    DPL2, DPPY, DPRP3, DPRP-3
  • Links
    NCBI Gene ID: 57628
    neXtProt AC: NX_Q8N608

  • Chr Location
    2q14.1; chr2:114442322-115845752 (+)  GRCh38.p2
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
  • All Mutations and Alleles
    5
  • Chemically induced (other)
    2
  • Radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    3 involving Dpp10
  • Incidental Mutations
    Mutagenetix , APF , CvDC
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    12
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
    6
  • Literature Summary
    2
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000020794 VEGA Gene Model | MGI Sequence Detail 724089 C57BL/6J ±  kb
transcript OTTMUST00000049175 VEGA | MGI Sequence Detail 15297 Not Applicable  
polypeptide OTTMUSP00000022738 VEGA | MGI Sequence Detail 800 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    13777 from dbSNP Build 142
Protein
Information
less
  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000006659 inactive dipeptidyl peptidase 10
  • InterPro Domains
    IPR029058 Alpha/Beta hydrolase fold
    IPR002469 Dipeptidylpeptidase IV, N-terminal domain
    IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain
Molecular
Reagents
less
  • All nucleic 6
    cDNA 6

    Microarray probesets 3
References
more
  • Summaries
    All 24
    Developmental Gene Expression 2
    Gene Ontology 7
    Phenotypes 5
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:226616 Araujo DJ, et al., FoxP1 orchestration of ASD-relevant signaling pathways in the striatum. Genes Dev. 2015 Oct 15;29(20):2081-96
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/13/2016
MGI 6.05 		The Jackson Laboratory