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Ipo11 Gene Detail
Summary
  • Symbol
    Ipo11
  • Name
    importin 11
  • Synonyms
    1700081H05Rik, 2510001A17Rik, E330021B14Rik, Ranbp11
  • Feature Type
    protein coding gene
  • IDs
    MGI:2442377
    NCBI Gene: 76582
  • Gene Overview
    MyGene.info: IPO11
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:106794439-106936958 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 13, 58.06 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    967 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2442377
protein coding gene Chr13:106794439-106936960 (-)
129S1/SvImJ MGP_129S1SvImJ_G0020916
protein coding gene Chr13:108969984-109129658 (-)
A/J MGP_AJ_G0020867
protein coding gene Chr13:104727756-104876491 (-)
AKR/J MGP_AKRJ_G0020842
protein coding gene Chr13:107910792-108055434 (-)
BALB/cJ MGP_BALBcJ_G0020867
protein coding gene Chr13:105433773-105581738 (-)
C3H/HeJ MGP_C3HHeJ_G0020656
protein coding gene Chr13:107665497-107818797 (-)
C57BL/6NJ MGP_C57BL6NJ_G0021301
protein coding gene Chr13:112288219-112437717 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0018871
protein coding gene Chr13:100183811-100316584 (-)
CAST/EiJ MGP_CASTEiJ_G0020175
protein coding gene Chr13:107157135-107312655 (-)
CBA/J MGP_CBAJ_G0020618
protein coding gene Chr13:116600577-116760026 (-)
DBA/2J MGP_DBA2J_G0020742
protein coding gene Chr13:104495027-104640955 (-)
FVB/NJ MGP_FVBNJ_G0020724
protein coding gene Chr13:103153954-103297626 (-)
LP/J MGP_LPJ_G0020816
protein coding gene Chr13:109046244-109212046 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0020752
protein coding gene Chr13:117070887-117229495 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0021340
protein coding gene Chr13:107331058-107479576 (-)
PWK/PhJ MGP_PWKPhJ_G0019928
protein coding gene Chr13:103147728-103297382 (-)
SPRET/EiJ MGP_SPRETEiJ_G0019750
protein coding gene Chr13:103578190-103740679 (-)
WSB/EiJ MGP_WSBEiJ_G0020233
protein coding gene Chr13:107877852-108037135 (-)



Homology
more
  • Human Ortholog
    IPO11, importin 11
  • Vertebrate Orthologs
    10
  • Human Ortholog
    IPO11, importin 11
    Orthology source: HomoloGene, HGNC
  • Synonyms
    RanBP11
  • Links
    NCBI Gene ID: 51194
    neXtProt AC: NX_Q9UI26
    UniProt: Q9UI26

  • Chr Location
    5q12.1; chr5:62412746-62628589 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 7089
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: IPO11
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000042590 Ensembl Gene Model | MGI Sequence Detail 142520 C57BL/6J ±  kb
    transcript ENSMUST00000186033 Ensembl | MGI Sequence Detail 4147 Not Applicable  
    polypeptide ENSMUSP00000140046 Ensembl | MGI Sequence Detail 984 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 13
      cDNA 13

      Microarray probesets 5
    Other
    Accession IDs
    less
    MGI:1920761, MGI:1923832, MGI:2145201, MGI:2145456
    References
    more
    • Summaries
      All 37
      Developmental Gene Expression 1
      Gene Ontology 6
      Phenotypes 12
    • Earliest
      J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-Le-Grand). 1999 Jul;45(5):737-50
    • Latest
      J:248576 Chen M, et al., The nuclear transport receptor Importin-11 is a tumor suppressor that maintains PTEN protein. J Cell Biol. 2017 Mar 6;216(3):641-656

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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    last database update
    11/06/2018
    MGI 6.13
    The Jackson Laboratory