About   Help   FAQ
Cd300lf Gene Detail
Summary
  • Symbol
    Cd300lf
  • Name
    CD300 molecule like family member F
  • Synonyms
    CLM-1, DIgR2, F730004D16Rik, IgSF13, IREM1, LMIR3, Pigr3
  • Feature Type
    protein coding gene
  • IDs
    MGI:2442359
    NCBI Gene: 246746
  • Gene Overview
    MyGene.info: CD300LF
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:115116214-115133992 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 80.59 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    196 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2442359
protein coding gene Chr11:115116214-115135823 (-)
129S1/SvImJ MGP_129S1SvImJ_G0019372
protein coding gene Chr11:119114262-119132216 (-)
A/J MGP_AJ_G0019341
protein coding gene Chr11:113916543-113934740 (-)
AKR/J MGP_AKRJ_G0019311
protein coding gene Chr11:117314095-117331873 (-)
BALB/cJ MGP_BALBcJ_G0019315
protein coding gene Chr11:114336201-114354354 (-)
C3H/HeJ MGP_C3HHeJ_G0019121
protein coding gene Chr11:117667112-117685140 (-)
C57BL/6NJ MGP_C57BL6NJ_G0019765
protein coding gene Chr11:122750984-122768656 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017387
protein coding gene Chr11:110961633-110980340 (-)
CAST/EiJ MGP_CASTEiJ_G0018676
protein coding gene Chr11:118970367-118988109 (-)
CBA/J MGP_CBAJ_G0019093
protein coding gene Chr11:127591410-127608958 (-)
DBA/2J MGP_DBA2J_G0019204
protein coding gene Chr11:113357517-113375241 (-)
FVB/NJ MGP_FVBNJ_G0019196
protein coding gene Chr11:112826541-112844420 (-)
LP/J MGP_LPJ_G0019274
protein coding gene Chr11:119494437-119512837 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0019229
protein coding gene Chr11:126783837-126801516 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0019803
protein coding gene Chr11:117974056-117991825 (-)
PWK/PhJ MGP_PWKPhJ_G0018440
protein coding gene Chr11:114632095-114650538 (-)
SPRET/EiJ MGP_SPRETEiJ_G0018232
protein coding gene Chr11:117719358-117737171 (-)
WSB/EiJ MGP_WSBEiJ_G0018728
protein coding gene Chr11:117916948-117937180 (-)



Homology
more
  • Human Ortholog
    CD300LF, CD300 molecule like family member f
  • Vertebrate Orthologs
    7
  • Human Ortholog
    CD300LF, CD300 molecule like family member f
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CD300f, CLM1, CLM-1, IgSF13, IREM1, IREM-1, LMIR3, NKIR
  • Links
    NCBI Gene ID: 146722
    neXtProt AC: NX_Q8TDQ1
    UniProt: Q8TDQ1

  • Chr Location
    17q25.1; chr17:74694308-74713059 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    14 phenotypes from 2 alleles in 2 genetic backgrounds
    14 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit increased severity of experimental autoimmune encephalomyelitis with increased demyelination.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000047798 Ensembl Gene Model | MGI Sequence Detail 17779 C57BL/6J ±  kb
    transcript ENSMUST00000106561 Ensembl | MGI Sequence Detail 1885 Not Applicable  
    polypeptide ENSMUSP00000102171 Ensembl | MGI Sequence Detail 337 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 19
      cDNA 19

      Microarray probesets 2
    References
    more
    • Summaries
      All 41
      Developmental Gene Expression 2
      Gene Ontology 9
      Phenotypes 14
    • Earliest
      J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
    • Latest
      J:260541 Wilen CB, et al., Tropism for tuft cells determines immune promotion of norovirus pathogenesis. Science. 2018 Apr 13;360(6385):204-208

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
    Citing These Resources
    Funding Information
    Warranty Disclaimer & Copyright Notice
    Send questions and comments to User Support.
    last database update
    11/06/2018
    MGI 6.13
    The Jackson Laboratory