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Csgalnact1 Gene Detail
Summary
  • Symbol
    Csgalnact1
  • Name
    chondroitin sulfate N-acetylgalactosaminyltransferase 1
  • Synonyms
    4732435N03Rik, CSGalNAcT-1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2442354
    NCBI Gene: 234356
  • Gene Overview
    MyGene.info: CSGALNACT1
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:68356781-68735146 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 8, 33.88 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    3398 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2442354
protein coding gene Chr8:68356781-68735675 (-)
129S1/SvImJ MGP_129S1SvImJ_G0033661
protein coding gene Chr8:68490715-68863279 (-)
A/J MGP_AJ_G0033643
protein coding gene Chr8:65712560-66074099 (-)
AKR/J MGP_AKRJ_G0033568
protein coding gene Chr8:67515233-67884089 (-)
BALB/cJ MGP_BALBcJ_G0033639
protein coding gene Chr8:65911156-66279965 (-)
C3H/HeJ MGP_C3HHeJ_G0033349
protein coding gene Chr8:68236081-68612603 (-)
C57BL/6NJ MGP_C57BL6NJ_G0034156
protein coding gene Chr8:71052553-71462215 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0031103
protein coding gene Chr8:60628144-60968730 (-)
CAST/EiJ MGP_CASTEiJ_G0032674
protein coding gene Chr8:67678816-68053805 (-)
CBA/J MGP_CBAJ_G0033327
protein coding gene Chr8:73741789-74131892 (-)
DBA/2J MGP_DBA2J_G0033481
protein coding gene Chr8:65442635-65806687 (-)
FVB/NJ MGP_FVBNJ_G0033422
protein coding gene Chr8:64600927-64960932 (-)
LP/J MGP_LPJ_G0033569
protein coding gene Chr8:68586354-68967464 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0033466
protein coding gene Chr8:76393141-76805820 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0034174
protein coding gene Chr8:67780721-68156562 (-)
PWK/PhJ MGP_PWKPhJ_G0032383
protein coding gene Chr8:64685780-65043464 (-)
SPRET/EiJ MGP_SPRETEiJ_G0032219
protein coding gene Chr8:66714395-67090346 (-)
WSB/EiJ MGP_WSBEiJ_G0032791
protein coding gene Chr8:68151941-68527455 (-)



Homology
more
  • Human Ortholog
    CSGALNACT1, chondroitin sulfate N-acetylgalactosaminyltransferase 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    CSGALNACT1, chondroitin sulfate N-acetylgalactosaminyltransferase 1
    Orthology source: HGNC, HomoloGene
  • Synonyms
    beta4GalNAcT, ChGn, ChGn-1, CSGalNAcT-1
  • Links
    NCBI Gene ID: 55790
    neXtProt AC: NX_Q8TDX6
    UniProt: Q8TDX6

  • Chr Location
    8p21.3; chr8:19404161-19757940 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    19 phenotypes from 3 alleles in 3 genetic backgrounds
    20 phenotypes from multigenic genotypes
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit decreased body weight and length, short limbs, and abnormal cartilage.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000036356 Ensembl Gene Model | MGI Sequence Detail 378366 C57BL/6J ±  kb
    transcript ENSMUST00000078350 Ensembl | MGI Sequence Detail 3943 Not Applicable  
    polypeptide ENSMUSP00000077459 Ensembl | MGI Sequence Detail 530 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 10
      cDNA 9
      Primer pair 1

      Microarray probesets 4
    References
    more
    • Summaries
      All 35
      Developmental Gene Expression 6
      Gene Ontology 5
      Phenotypes 13
    • Earliest
      J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
    • Latest
      J:256718 Shimbo M, et al., Postnatal lethality and chondrodysplasia in mice lacking both chondroitin sulfate N-acetylgalactosaminyltransferase-1 and -2. PLoS One. 2017;12(12):e0190333

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
    Citing These Resources
    Funding Information
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    last database update
    12/04/2018
    MGI 6.13
    The Jackson Laboratory