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Tmprss11f
Gene Detail
Symbol

Name
ID
Tmprss11f
transmembrane protease, serine 11f
MGI:2442348
Synonyms
4732406D01Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 5
43.56 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr5:86521898-86632424 bp, - strand
From VEGA annotation of GRCm38

  110527 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:65356  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog

HCOP human homology predictions: TMPRSS11F
Protein SuperFamily: transmembrane serine protease, TMPRSS11A type
Gene Tree: Tmprss11f

Human
homologs
TMPRSS11F, transmembrane protease, serine 11F
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 389208
neXtProt AC: NX_Q6ZWK6

Human Chr (Location): 4q13.2; chr4:68053198-68129869 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
Incidental mutations (data from Mutagenetix , APF , CvDC )
Interactions
Tmprss11f interacts with 312 markers (Mir1b, Mir7-1, Mir7-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (10 annotations)
Process proteolysis
Component extracellular region, integral component of membrane, ...
Function hydrolase activity, peptidase activity, ...
External Resources: FuncBase
Expression
cDNA source data(8)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase tmprss11f    NEW 
Molecular
reagents
All nucleic(8) cDNA(8)
Microarray probesets(2)
Other database
links
VEGA Gene Model OTTMUSG00000035103 (Evidence)
Ensembl Gene Model ENSMUSG00000048764 (Evidence)
Entrez Gene 243083 (Evidence)
UniGene 106867
DFCI TC1587005, TC1670459, TC1628488
DoTS DT.101713209, DT.91419343
NIA Mouse Gene Index U096772
EC 3.4.21.-
Consensus CDS Project CCDS39125.1
International Mouse Phenotyping Consortium Status Tmprss11f
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000035103 VEGA Gene Model | MGI Sequence Detail 110527 C57BL/6J ±  kb
transcript OTTMUST00000089302 VEGA | MGI Sequence Detail 3605 Not Applicable 
polypeptide OTTMUSP00000048792 VEGA | MGI Sequence Detail 439 Not Applicable 

For the selected sequences
All sequences(32) RefSeq(6) UniProt(1)
Polymorphisms
SNPs within 2kb(561 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001254 Peptidase S1
InterPro IPR001314 Peptidase S1A, chymotrypsin-type
InterPro IPR017329 Peptidase S1A, HAT/DESC1
InterPro IPR018114 Peptidase S1, trypsin family, active site
InterPro IPR000082 SEA domain
InterPro IPR009003 Trypsin-like cysteine/serine peptidase domain
Protein Ontology PR:000016453 transmembrane protease serine 11F
References
(Earliest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(23)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/28/2015
MGI 5.22
The Jackson Laboratory