About   Help   FAQ
Uspl1 Gene Detail
Summary
  • Symbol
    Uspl1
  • Name
    ubiquitin specific peptidase like 1
  • Synonyms
    E430026A01Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2442342
    NCBI Gene: 231915
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:149184560-149215434 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 89.18 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    102 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2442342
protein coding gene Chr5:149184350-149215434 (.)
129S1/SvImJ MGP_129S1SvImJ_G0030400
protein coding gene Chr5:154998387-155028880 (+)
A/J MGP_AJ_G0030373
protein coding gene Chr5:148389985-148421546 (+)
AKR/J MGP_AKRJ_G0030300
protein coding gene Chr5:152970176-153002261 (+)
BALB/cJ MGP_BALBcJ_G0030382
protein coding gene Chr5:149639913-149670919 (+)
C3H/HeJ MGP_C3HHeJ_G0030096
protein coding gene Chr5:153959601-153990071 (+)
C57BL/6NJ MGP_C57BL6NJ_G0030837
protein coding gene Chr5:160700000-160731689 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0028050
protein coding gene Chr5:142747148-142777934 (+)
CAST/EiJ MGP_CASTEiJ_G0029498
protein coding gene Chr5:153567484-153598241 (+)
CBA/J MGP_CBAJ_G0030074
protein coding gene Chr5:167423887-167454395 (+)
DBA/2J MGP_DBA2J_G0030218
protein coding gene Chr5:148046489-148076992 (+)
FVB/NJ MGP_FVBNJ_G0030172
protein coding gene Chr5:147297656-147329024 (+)
LP/J MGP_LPJ_G0030305
protein coding gene Chr5:155696086-155726915 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0030208
protein coding gene Chr5:169578058-169609266 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0030867
protein coding gene Chr5:152896826-152927966 (+)
PWK/PhJ MGP_PWKPhJ_G0029212
protein coding gene Chr5:147199570-147231136 (+)
SPRET/EiJ MGP_SPRETEiJ_G0029048
protein coding gene Chr5:150199355-150230166 (+)
WSB/EiJ MGP_WSBEiJ_G0029575
protein coding gene Chr5:153713018-153744503 (+)



Homology
more
  • Human Ortholog
    USPL1, ubiquitin specific peptidase like 1
  • Vertebrate Orthologs
    8
  • Human Ortholog
    USPL1, ubiquitin specific peptidase like 1
    Orthology source: HGNC, HomoloGene
  • Synonyms
    bA121O19.1, C13orf22, D13S106E
  • Links
    NCBI Gene ID: 10208
    neXtProt AC: NX_Q5W0Q7
    UniProt: Q5W0Q7

  • Chr Location
    13q12.3; chr13:30617397-30660770 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 231915 NCBI Gene Model | MGI Sequence Detail 30875 C57BL/6J ±  kb
transcript NM_001115153 RefSeq | MGI Sequence Detail 3949 C57BL/6  
polypeptide Q3ULM6 UniProt | EBI | MGI Sequence Detail 1089 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    6 Sequences
  • EC
  • InterPro Domains
    IPR029388 Domain of unknown function DUF4650
    IPR038765 Papain-like cysteine peptidase superfamily
    IPR028890 Ubiquitin-specific peptidase-like, SUMO isopeptidase
    IPR028889 Ubiquitin specific protease domain
    IPR033505 USPL1 peptidase
Molecular
Reagents
less
  • All nucleic 137
    cDNA 132
    Primer pair 5

    Microarray probesets 3
References
more
  • Summaries
    All 30
    Developmental Gene Expression 3
    Gene Ontology 3
    Phenotypes 8
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:244597 Cui W, et al., Towards Functional Annotation of the Preimplantation Transcriptome: An RNAi Screen in Mammalian Embryos. Sci Rep. 2016 Nov 21;6:37396

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
12/04/2018
MGI 6.13
The Jackson Laboratory