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Uspl1 Gene Detail
Summary
  • Symbol
    Uspl1
  • Name
    ubiquitin specific peptidase like 1
  • Synonyms
    E430026A01Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2442342
    NCBI Gene: 231915
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:149121338-149152246 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 5, 89.18 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    739 from dbSNP Build 142
  • Strain Annotations
    27
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2442342
protein coding gene Chr5:149121160-149152246 (+)
129S1/SvImJ ENSMUSG00200010701
protein coding gene Chr5:142965955-142987548 (+)
129S1/SvImJ ENSMUSGG00200054570
protein coding gene Chr5:142959823-142966555 (+)
A/J ENSMUSGG00195055321
protein coding gene Chr5:142569211-142575943 (+)
A/J ENSMUSG00195004753
protein coding gene Chr5:142575343-142596936 (+)
AKR/J ENSMUSGG00220054478
protein coding gene Chr5:141572870-141579598 (+)
AKR/J ENSMUSG00220014786
protein coding gene Chr5:141578998-141600552 (+)
BALB/cJ ENSMUSGG00180055392
protein coding gene Chr5:142971600-142978332 (+)
BALB/cJ ENSMUSG00180003103
protein coding gene Chr5:142977732-142999325 (+)
C3H/HeJ ENSMUSGG00175054936
protein coding gene Chr5:144812430-144819162 (+)
C3H/HeJ ENSMUSG00175010886
protein coding gene Chr5:144818562-144840155 (+)
C57BL/6NJ ENSMUSG00215000050
protein coding gene Chr5:142521685-142543276 (+)
C57BL/6NJ ENSMUSGG00215055727
protein coding gene Chr5:142515553-142522285 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0028050
protein coding gene Chr5:142747148-142777934 (+)
CAST/EiJ no annotation
CBA/J ENSMUSGG00210054916
protein coding gene Chr5:143705730-143712462 (+)
CBA/J ENSMUSG00210000448
protein coding gene Chr5:143711862-143733455 (+)
DBA/2J ENSMUSG00185037391
protein coding gene Chr5:146681986-146703579 (+)
DBA/2J ENSMUSGG00185057794
protein coding gene Chr5:146675854-146682586 (+)
FVB/NJ ENSMUSG00205024059
protein coding gene Chr5:142356621-142378215 (+)
FVB/NJ ENSMUSGG00205054159
protein coding gene Chr5:142350489-142357221 (+)
JF1/MsJ no annotation
LP/J ENSMUSG00230028146
protein coding gene Chr5:150682680-150704247 (+)
LP/J ENSMUSGG00230055481
protein coding gene Chr5:150676548-150683280 (+)
NOD/ShiLtJ ENSMUSGG00190054910
protein coding gene Chr5:142317496-142324228 (+)
NOD/ShiLtJ ENSMUSG00190005486
protein coding gene Chr5:142323628-142345229 (+)
NZO/HlLtJ ENSMUSG00225007897
protein coding gene Chr5:158427813-158449406 (+)
NZO/HlLtJ ENSMUSGG00225055643
protein coding gene Chr5:158421681-158428413 (+)
PWK/PhJ no annotation
SPRET/EiJ ENSMSPG00010006442
protein coding gene Chr5:144207865-144238638 (+)
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    USPL1, ubiquitin specific peptidase like 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    USPL1, ubiquitin specific peptidase like 1
  • Synonyms
    bA121O19.1, C13orf22, D13S106E
  • Links
    NCBI Gene ID: 10208
    UniProt: Q5W0Q7

  • Chr Location
    13q12.3; chr13:30617693-30660770 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 231915 NCBI Gene Model | MGI Sequence Detail 30909 C57BL/6J ±  kb
transcript NM_001115153 RefSeq | MGI Sequence Detail 3949 C57BL/6  
polypeptide Q3ULM6 UniProt | EBI | MGI Sequence Detail 1089 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 137
    cDNA 132
    Primer pair 5
    Antibodies 1

    Microarray probesets 3
References
more
  • Summaries
    All 38
    Developmental Gene Expression 3
    Gene Ontology 6
    Phenotypes 11
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:244597 Cui W, et al., Towards Functional Annotation of the Preimplantation Transcriptome: An RNAi Screen in Mammalian Embryos. Sci Rep. 2016 Nov 21;6:37396

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
09/08/2026
MGI 6.24
The Jackson Laboratory