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Lrrc1 Gene Detail
Summary
  • Symbol
    Lrrc1
  • Name
    leucine rich repeat containing 1
  • Synonyms
    A430093J20Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2442313
    NCBI Gene: 214345
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:77430823-77544852 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 9, 43.36 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1159 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2442313
protein coding gene Chr9:77430823-77544870 (-)
129S1/SvImJ MGP_129S1SvImJ_G0035052
protein coding gene Chr9:77864650-77985296 (-)
A/J MGP_AJ_G0035033
protein coding gene Chr9:75140275-75258224 (-)
AKR/J MGP_AKRJ_G0034962
protein coding gene Chr9:76921047-77038968 (-)
BALB/cJ MGP_BALBcJ_G0035025
protein coding gene Chr9:74823680-74938935 (-)
C3H/HeJ MGP_C3HHeJ_G0034734
protein coding gene Chr9:77429829-77563675 (-)
C57BL/6NJ MGP_C57BL6NJ_G0035543
protein coding gene Chr9:79943935-80062473 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0032454
protein coding gene Chr9:74410189-74524505 (-)
CAST/EiJ MGP_CASTEiJ_G0034056
protein coding gene Chr9:77785775-77903701 (-)
CBA/J MGP_CBAJ_G0034706
protein coding gene Chr9:82717550-82844145 (-)
DBA/2J MGP_DBA2J_G0034866
protein coding gene Chr9:74798584-74913927 (-)
FVB/NJ MGP_FVBNJ_G0034808
protein coding gene Chr9:74055934-74170645 (-)
LP/J MGP_LPJ_G0034947
protein coding gene Chr9:78098232-78215040 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0034849
protein coding gene Chr9:83922444-84047770 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0035566
protein coding gene Chr9:77107428-77219665 (-)
PWK/PhJ MGP_PWKPhJ_G0033760
protein coding gene Chr9:75055737-75168781 (-)
SPRET/EiJ MGP_SPRETEiJ_G0033593
protein coding gene Chr9:77359458-77471457 (-)
WSB/EiJ MGP_WSBEiJ_G0034168
protein coding gene Chr9:77021866-77137480 (-)



Homology
more
  • Human Ortholog
    LRRC1, leucine rich repeat containing 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    LRRC1, leucine rich repeat containing 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    dJ523E19.1, LANO
  • Links
    NCBI Gene ID: 55227
    neXtProt AC: NX_Q9BTT6
    UniProt: Q9BTT6

  • Chr Location
    6p12.1; chr6:53794497-53924125 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 44445
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: LRRC1
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 214345 NCBI Gene Model | MGI Sequence Detail 114030 C57BL/6J ±  kb
transcript NM_001146048 RefSeq | MGI Sequence Detail 3103 Not Specified  
polypeptide Q80VQ1 UniProt | EBI | MGI Sequence Detail 524 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 15
    cDNA 15

    Microarray probesets 4
Other
Accession IDs
less
MGI:2143193
References
more
  • Summaries
    All 33
    Gene Ontology 3
    Phenotypes 8
  • Earliest
    J:12013 Russell LB, Definition of functional units in a small chromosomal segment of the mouse and its use in interpreting the nature of radiation-induced mutations. Mutat Res. 1971 Jan;11(1):107-23
  • Latest
    J:237217 Kravic B, et al., LAP proteins are localized at the post-synaptic membrane of neuromuscular junctions and appear to modulate synaptic morphology and transmission. J Neurochem. 2016 Nov;139(3):381-395

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
08/06/2019
MGI 6.14
The Jackson Laboratory