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Arl15 Gene Detail
Summary
  • Symbol
    Arl15
  • Name
    ADP-ribosylation factor-like 15
  • Synonyms
    Arfrp2, C230032K13Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2442308
    NCBI Gene: 218639
  • Gene Overview
    MyGene.info: ARL15
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:113794508-114157462 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 13, 64.02 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    4125 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2442308
protein coding gene Chr13:113794505-114157462 (.)
129S1/SvImJ MGP_129S1SvImJ_G0020954
protein coding gene Chr13:116459413-116845044 (+)
A/J MGP_AJ_G0020904
protein coding gene Chr13:111797960-112166100 (+)
AKR/J MGP_AKRJ_G0020879
protein coding gene Chr13:115133965-115498465 (+)
BALB/cJ MGP_BALBcJ_G0020904
protein coding gene Chr13:112471612-112836403 (+)
C3H/HeJ MGP_C3HHeJ_G0020693
protein coding gene Chr13:114938422-115309957 (+)
C57BL/6NJ MGP_C57BL6NJ_G0021340
protein coding gene Chr13:119900826-120276271 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0018909
protein coding gene Chr13:107039611-107402324 (+)
CAST/EiJ MGP_CASTEiJ_G0020212
protein coding gene Chr13:114605496-114985480 (+)
CBA/J MGP_CBAJ_G0020655
protein coding gene Chr13:124486315-124874588 (+)
DBA/2J MGP_DBA2J_G0020778
protein coding gene Chr13:111476343-111838136 (+)
FVB/NJ MGP_FVBNJ_G0020762
protein coding gene Chr13:110158567-110530599 (+)
LP/J MGP_LPJ_G0020854
protein coding gene Chr13:116487725-116863881 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0020790
protein coding gene Chr13:124756932-125155573 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0021376
protein coding gene Chr13:114630131-115009652 (+)
PWK/PhJ no annotation
SPRET/EiJ MGP_SPRETEiJ_G0019787
protein coding gene Chr13:110933366-111309658 (+)
WSB/EiJ MGP_WSBEiJ_G0020270
protein coding gene Chr13:115219101-115598493 (+)



Homology
more
  • Human Ortholog
    ARL15, ADP ribosylation factor like GTPase 15
  • Vertebrate Orthologs
    10
  • Human Ortholog
    ARL15, ADP ribosylation factor like GTPase 15
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ARFRP2
  • Links
    NCBI Gene ID: 54622
    neXtProt AC: NX_Q9NXU5
    UniProt: Q9NXU5

  • Chr Location
    5q11.2; chr5:53883942-54310590 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    16 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 218639 NCBI Gene Model | MGI Sequence Detail 362955 C57BL/6J ±  kb
transcript NM_172595 RefSeq | MGI Sequence Detail 3376 C57BL/6  
polypeptide Q8BGR6 UniProt | EBI | MGI Sequence Detail 204 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000004279 ADP-ribosylation factor-like protein 15
  • InterPro Domains
    IPR027417 P-loop containing nucleoside triphosphate hydrolase
    IPR006689 Small GTPase superfamily, ARF/SAR type
Molecular
Reagents
less
  • All nucleic 23
    cDNA 23

    Microarray probesets 4
References
more
  • Summaries
    All 39
    Gene Ontology 2
    Phenotypes 16
  • Earliest
    J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-Le-Grand). 1999 Jul;45(5):737-50
  • Latest
    J:251423 Zhao J, et al., ADP-ribosylation factor-like GTPase 15 enhances insulin-induced AKT phosphorylation in the IR/IRS1/AKT pathway by interacting with ASAP2 and regulating PDPK1 activity. Biochem Biophys Res Commun. 2017 May 13;486(4):865-871

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory