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5430435G22Rik
Gene Detail
 Symbol
Name
ID
5430435G22Rik
RIKEN cDNA 5430435G22 gene
MGI:2442295
Synonyms Rab7b
Feature Type protein coding gene
Genetic Map
Chromosome 1
57.18 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr1:131688695-131715439 bp, + strand
From VEGA annotation of GRCm38

  26745 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:64833  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog

Protein SuperFamily: Ras-related protein Rab
Gene Tree: 5430435G22Rik

Human
homologs
Human Homolog RAB7B, RAB7B, member RAS oncogene family
NCBI Gene ID 338382
neXtProt AC  NX_Q96AH8
Human Synonyms  RAB7
Human Chr (Location)  1q32; chr1:205976740-206003466 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Gene trapped(1) Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
Interactions
5430435G22Rik interacts with 235 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (23 annotations)
Process late endosome to Golgi transport, negative regulation of toll-like receptor 4 signaling pathway, ...
Component cytoplasmic vesicle, endosome, ...
Function GTP binding, nucleotide binding
External Resources: FuncBase
Expression
cDNA source data(5)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(5) cDNA(5)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000026757 (Evidence)
Ensembl Gene ModelENSMUSG00000052688 (Evidence)
Entrez Gene226421 (Evidence)
DFCITC1581683, TC1589471, TC1594023
DoTSDT.40185163, DT.91569211, DT.97365829, DT.99839311
NIA Mouse Gene IndexU000783
Consensus CDS ProjectCCDS15272.1
International Mouse Knockout Project Status5430435G22Rik
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000026757 VEGA Gene Model | MGI Sequence Detail 26745 C57BL/6J ±  kb
transcript OTTMUST00000066181 VEGA | MGI Sequence Detail 4498 Not Applicable 
polypeptide OTTMUSP00000033121 VEGA | MGI Sequence Detail 199 Not Applicable 

For the selected sequences
All sequences(59) RefSeq(14) UniProt(4)
Polymorphisms SNPs within 2kb(340 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
InterPro IPR001806 Small GTPase superfamily
InterPro IPR003579 Small GTPase superfamily, Rab type
InterPro IPR005225 Small GTP-binding protein domain
Protein Ontology PR:000013640 ras-related protein Rab-7b
References (Earliest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(27)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
08/26/2014
MGI 5.19
The Jackson Laboratory