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Rab7b
Gene Detail
Symbol

Name
ID
Rab7b
RAB7B, member RAS oncogene family
MGI:2442295
Synonyms
5430435G22Rik, Rab7b
Feature Type
protein coding gene
Genetic Map
Chromosome 1
57.18 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr1:131688695-131715439 bp, + strand
From VEGA annotation of GRCm38

  26745 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:64833  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog

HCOP human homology predictions: RAB7B
Protein SuperFamily: Ras-related protein Rab
Gene Tree: Rab7b

Human
homologs
RAB7B, RAB7B, member RAS oncogene family
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 338382
neXtProt AC: NX_Q96AH8

Human Synonyms: RAB7

Human Chr (Location): 1q32; chr1:205976740-206003495 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Gene trapped(1) Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Rab7b interacts with 234 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (30 annotations)
Process endosome to lysosome transport, intracellular protein transport, ...
Component cytoplasmic vesicle, endosome, ...
Function GTPase activity, GTP binding, ...
External Resources: FuncBase
Expression
cDNA source data(5)
Other mouse links: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(5) cDNA(5)
Microarray probesets(4)
Other database
links
VEGA Gene Model OTTMUSG00000026757 (Evidence)
Ensembl Gene Model ENSMUSG00000052688 (Evidence)
Entrez Gene 226421 (Evidence)
DFCI TC1594023, TC1581683, TC1589471
DoTS DT.40185163, DT.91569211, DT.99839311, DT.97365829
NIA Mouse Gene Index U000783
Consensus CDS Project CCDS15272.1
International Mouse Phenotyping Consortium Status Rab7b
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000026757 VEGA Gene Model | MGI Sequence Detail 26745 C57BL/6J ±  kb
transcript OTTMUST00000066181 VEGA | MGI Sequence Detail 4498 Not Applicable 
polypeptide OTTMUSP00000033121 VEGA | MGI Sequence Detail 199 Not Applicable 

For the selected sequences
All sequences(59) RefSeq(14) UniProt(4)
Polymorphisms
SNPs within 2kb(340 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
InterPro IPR001806 Small GTPase superfamily
InterPro IPR003579 Small GTPase superfamily, Rab type
InterPro IPR005225 Small GTP-binding protein domain
Protein Ontology PR:000013640 ras-related protein Rab-7b
References
(Earliest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(27)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory