5430435G22Rik
Gene Detail

Symbol Name ID

5430435G22Rik RIKEN cDNA 5430435G22 gene MGI:2442295

Synonyms

Rab7b

Feature Type

protein coding gene

Genetic Map

Chromosome 1

57.18 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)

Sequence Map

Chr1:131688695-131713542 bp, + strand From VEGA annotation of GRCm38   24848 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:64833  Vertebrate Homology Class
1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken

Protein SuperFamily: Ras-related protein Rab
Gene Tree: 5430435G22Rik

Alleles and phenotypes

All alleles(2) : Targeted(1) Gene trapped(1)

Gene Ontology (GO) classifications

All GO classifications: (13 annotations)

Process	negative regulation of toll-like receptor 4 signaling pathway, negative regulation of toll-like receptor 9 signaling pathway, ...
Component	endosome, Golgi apparatus, ...
Function	GTP binding, nucleotide binding

External Resources: FuncBase

Expression

cDNA source data(5)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(5) cDNA(5)
Microarray probesets(4)

Other database links

VEGA Gene Model	OTTMUSG00000026757 (Evidence)
Ensembl Gene Model	ENSMUSG00000052688 (Evidence)
Entrez Gene	226421 (Evidence)
DFCI	TC1581683, TC1589471, TC1594023
DoTS	DT.40185163, DT.91569211, DT.97365829, DT.99839311
NIA Mouse Gene Index	U000783
Consensus CDS Project	CCDS15272.1
International Mouse Knockout Project Status	5430435G22Rik

Sequences

Length	Strain/Species
genomic	OTTMUSG00000026757	VEGA Gene Model | MGI Sequence Detail	24848	C57BL/6J
transcript	OTTMUST00000066181	VEGA | MGI Sequence Detail	2601	Not Applicable
polypeptide	OTTMUSP00000033121	VEGA | MGI Sequence Detail	199	Not Applicable

All sequences(45) RefSeq(2) UniProt(3)

Polymorphisms

SNPs(218 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR001806	Small GTPase superfamily
InterPro	IPR003579	Small GTPase superfamily, Rab type
InterPro	IPR005225	Small GTP-binding protein domain
Protein Ontology	PR:000013640	ras-related protein Rab-7b

References

(Earliest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(26)