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Kctd7 Gene Detail
Summary
  • Symbol
    Kctd7
  • Name
    potassium channel tetramerisation domain containing 7
  • Synonyms
    9430010P06Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2442265
    NCBI Gene: 212919
  • Gene Overview
    MyGene.info: KCTD7
Location & Maps
more
  • Sequence Map
    Chr5:130144861-130155806 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      10946 bp   ±  kb flank

  • Genome Browsers
Homology
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  • Human Ortholog
    KCTD7, potassium channel tetramerization domain containing 7
  • Vertebrate Orthologs
    9
  • Human Ortholog
    KCTD7, potassium channel tetramerization domain containing 7
    Orthology source: HGNC, HomoloGene
  • Synonyms
    CLN14, EPM3
  • Links
    NCBI Gene ID: 154881
    neXtProt AC: NX_Q96MP8

  • Chr Location
    7q11.21; chr7:66628881-66643229 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 17687
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: KCTD7
  • Gene Tree
Human Diseases
more
  • Diseases
    1 with human KCTD7 associations

Human Disease Mouse Models
       Epilepsy, Progressive Myoclonic, 3, with or without Intracellular Inclusions; EPM3   OMIM: 611726
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    7 phenotype references
  • All Mutations and Alleles
    4
  • Chemically induced (other)
    1
  • Radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    2 involving Kctd7
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000026833 VEGA Gene Model | MGI Sequence Detail 10946 C57BL/6J ±  kb
transcript OTTMUST00000066362 VEGA | MGI Sequence Detail 4291 Not Applicable  
polypeptide OTTMUSP00000033249 VEGA | MGI Sequence Detail 289 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    67 from dbSNP Build 142
Protein
Information
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  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000029577 BTB/POZ domain-containing protein KCTD7
  • InterPro Domains
    IPR000210 BTB/POZ domain
    IPR003131 Potassium channel tetramerisation-type BTB domain
    IPR011333 SKP1/BTB/POZ domain
Molecular
Reagents
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  • All nucleic 17
    Genomic 1
    cDNA 16

    Microarray probesets 4
References
more
  • Summaries
    All 23
    Gene Ontology 2
    Phenotypes 7
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
05/17/2016
MGI 6.03
The Jackson Laboratory