About   Help   FAQ
Kctd7 Gene Detail
Summary
  • Symbol
    Kctd7
  • Name
    potassium channel tetramerisation domain containing 7
  • Synonyms
    9430010P06Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2442265
    NCBI Gene: 212919
  • Gene Overview
    MyGene.info: KCTD7
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:130144861-130155806 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 68.72 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    67 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2442265
protein coding gene Chr5:130143750-130155808 (.)
129S1/SvImJ MGP_129S1SvImJ_G0030141
protein coding gene Chr5:134259375-134270312 (+)
A/J MGP_AJ_G0030109
protein coding gene Chr5:128599422-128610357 (+)
AKR/J MGP_AKRJ_G0030042
protein coding gene Chr5:132772082-132783013 (+)
BALB/cJ MGP_BALBcJ_G0030119
protein coding gene Chr5:129952259-129963210 (+)
C3H/HeJ MGP_C3HHeJ_G0029835
protein coding gene Chr5:133339818-133350757 (+)
C57BL/6NJ MGP_C57BL6NJ_G0030572
protein coding gene Chr5:139406881-139417796 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0027797
protein coding gene Chr5:122982496-122994430 (+)
CAST/EiJ MGP_CASTEiJ_G0029245
protein coding gene Chr5:132658811-132669783 (+)
CBA/J MGP_CBAJ_G0029805
protein coding gene Chr5:144835236-144846179 (+)
DBA/2J MGP_DBA2J_G0029956
protein coding gene Chr5:128564865-128575810 (+)
FVB/NJ MGP_FVBNJ_G0029911
protein coding gene Chr5:127657348-127668582 (+)
LP/J MGP_LPJ_G0030044
protein coding gene Chr5:134770392-134781298 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0029943
protein coding gene Chr5:148168455-148179384 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0030612
protein coding gene Chr5:132472426-132483376 (+)
PWK/PhJ MGP_PWKPhJ_G0028959
protein coding gene Chr5:127504323-127515380 (+)
SPRET/EiJ MGP_SPRETEiJ_G0028795
protein coding gene Chr5:130041299-130053909 (+)
WSB/EiJ MGP_WSBEiJ_G0029318
protein coding gene Chr5:133178859-133189765 (+)



Homology
more
  • Human Ortholog
    KCTD7, potassium channel tetramerization domain containing 7
  • Vertebrate Orthologs
    9
  • Human Ortholog
    KCTD7, potassium channel tetramerization domain containing 7
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CLN14, EPM3
  • Links
    NCBI Gene ID: 154881
    neXtProt AC: NX_Q96MP8
    UniProt: Q96MP8

  • Chr Location
    7q11.21; chr7:66628881-66643229 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 17687
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: KCTD7
  • Gene Tree
Human Diseases
more
  • Diseases
    1 with human KCTD7 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000034110 Ensembl Gene Model | MGI Sequence Detail 10946 C57BL/6J ±  kb
transcript ENSMUST00000040616 Ensembl | MGI Sequence Detail 4291 Not Applicable  
polypeptide ENSMUSP00000044568 Ensembl | MGI Sequence Detail 289 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 18
    Genomic 2
    cDNA 16

    Microarray probesets 4
References
more
  • Summaries
    All 30
    Gene Ontology 4
    Phenotypes 7
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:252002 Moen MN, et al., Pathogenic variants in KCTD7 perturb neuronal K+ fluxes and glutamine transport. Brain. 2016 Dec;139(Pt 12):3109-3120

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/06/2018
MGI 6.13
The Jackson Laboratory