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N4bp3 Gene Detail
Summary
  • Symbol
    N4bp3
  • Name
    NEDD4 binding protein 3
  • Synonyms
    C330016O10Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2442218
    NCBI Gene: 212706
  • Alliance
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:51643063-51650842 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 31.19 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    30 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2442218
protein coding gene Chr11:51643063-51651073 (-)
129S1/SvImJ MGP_129S1SvImJ_G0018272
protein coding gene Chr11:50895884-50903674 (-)
A/J MGP_AJ_G0018241
protein coding gene Chr11:48980407-48988283 (-)
AKR/J MGP_AKRJ_G0018211
protein coding gene Chr11:50513766-50524854 (-)
BALB/cJ MGP_BALBcJ_G0018212
protein coding gene Chr11:49274720-49282481 (-)
C3H/HeJ MGP_C3HHeJ_G0018023
protein coding gene Chr11:50547318-50558269 (-)
C57BL/6NJ MGP_C57BL6NJ_G0018662
protein coding gene Chr11:52438700-52446473 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0016314
protein coding gene Chr11:46543961-46551697 (-)
CAST/EiJ MGP_CASTEiJ_G0017587
protein coding gene Chr11:50540862-50548656 (-)
CBA/J MGP_CBAJ_G0017998
protein coding gene Chr11:54892917-54900685 (-)
DBA/2J MGP_DBA2J_G0018105
protein coding gene Chr11:48688275-48696631 (-)
FVB/NJ MGP_FVBNJ_G0018100
protein coding gene Chr11:48396183-48405691 (-)
LP/J MGP_LPJ_G0018181
protein coding gene Chr11:51316864-51325568 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0018123
protein coding gene Chr11:56304611-56312404 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0018705
protein coding gene Chr11:50614433-50622236 (-)
PWK/PhJ MGP_PWKPhJ_G0017363
protein coding gene Chr11:49205705-49213627 (-)
SPRET/EiJ MGP_SPRETEiJ_G0017158
protein coding gene Chr11:50348365-50356342 (-)
WSB/EiJ MGP_WSBEiJ_G0017635
protein coding gene Chr11:50267008-50276281 (-)



Homology
more
  • Human Ortholog
    N4BP3, NEDD4 binding protein 3
  • Vertebrate Orthologs
    11
  • Human Ortholog
    N4BP3, NEDD4 binding protein 3
    Orthology source: HomoloGene, HGNC
  • Synonyms
    LZTS4
  • Links
    NCBI Gene ID: 23138
    neXtProt AC: NX_O15049
    UniProt: O15049

  • Chr Location
    5q35.3; chr5:178113506-178127034 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 17124
    1 human;1 mouse;2 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: N4BP3
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000001053 Ensembl Gene Model | MGI Sequence Detail 7780 C57BL/6J ±  kb
transcript ENSMUST00000001080 Ensembl | MGI Sequence Detail 2367 Not Applicable  
polypeptide ENSMUSP00000001080 Ensembl | MGI Sequence Detail 537 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 47
    cDNA 47

    Microarray probesets 3
References
more
  • Summaries
    All 33
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 12
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:236599 Dickinson ME, et al., High-throughput discovery of novel developmental phenotypes. Nature. 2016 Sep 14;537(7621):508-514

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
09/10/2019
MGI 6.14
The Jackson Laboratory