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Taf5 Gene Detail
Summary
  • Symbol
    Taf5
  • Name
    TATA-box binding protein associated factor 5
  • Synonyms
    6330528C20Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2442144
    NCBI Gene: 226182
  • Gene Overview
    MyGene.info: TAF5
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:47067748-47083479 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 19, 39.19 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    100 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2442144
protein coding gene Chr19:47067748-47083479 (.)
129S1/SvImJ MGP_129S1SvImJ_G0025221
protein coding gene Chr19:46842565-46858868 (+)
A/J MGP_AJ_G0025197
protein coding gene Chr19:44502486-44518247 (+)
AKR/J MGP_AKRJ_G0025166
protein coding gene Chr19:45959389-45978088 (+)
BALB/cJ MGP_BALBcJ_G0025192
protein coding gene Chr19:44552211-44568476 (+)
C3H/HeJ MGP_C3HHeJ_G0024952
protein coding gene Chr19:46139336-46155066 (+)
C57BL/6NJ MGP_C57BL6NJ_G0025635
protein coding gene Chr19:47966015-47981756 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0023049
protein coding gene Chr19:43746362-43761551 (+)
CAST/EiJ MGP_CASTEiJ_G0024417
protein coding gene Chr19:45950022-45966951 (+)
CBA/J MGP_CBAJ_G0024932
protein coding gene Chr19:50397577-50417011 (+)
DBA/2J MGP_DBA2J_G0025064
protein coding gene Chr19:44315850-44334506 (+)
FVB/NJ MGP_FVBNJ_G0025025
protein coding gene Chr19:44106942-44124401 (+)
LP/J MGP_LPJ_G0025150
protein coding gene Chr19:46738075-46754483 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0025056
protein coding gene Chr19:49689097-49706307 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0025693
protein coding gene Chr19:46077364-46093900 (+)
PWK/PhJ MGP_PWKPhJ_G0024166
protein coding gene Chr19:44279750-44296240 (+)
SPRET/EiJ MGP_SPRETEiJ_G0023970
protein coding gene Chr19:44729480-44747690 (+)
WSB/EiJ MGP_WSBEiJ_G0024487
protein coding gene Chr19:46221795-46239533 (+)



Homology
more
  • Human Ortholog
    TAF5, TATA-box binding protein associated factor 5
  • Vertebrate Orthologs
    10
  • Human Ortholog
    TAF5, TATA-box binding protein associated factor 5
    Orthology source: HomoloGene, HGNC
  • Synonyms
    TAF2D, TAFII100, TAF(II)100, TAFII-100
  • Links
    NCBI Gene ID: 6877
    neXtProt AC: NX_Q15542
    UniProt: Q15542

  • Chr Location
    10q24.33; chr10:103367953-103389065 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 5064
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: TAF5
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 226182 NCBI Gene Model | MGI Sequence Detail 15732 C57BL/6J ±  kb
transcript NM_177342 RefSeq | MGI Sequence Detail 3258 C57BL/6  
polypeptide Q8C092 UniProt | EBI | MGI Sequence Detail 801 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR020472 G-protein beta WD-40 repeat
    IPR006594 LIS1 homology motif
    IPR007582 TFIID subunit TAF5, NTD2 domain
    IPR037264 TFIID subunit TAF5, NTD2 domain superfamily
    IPR037783 Transcription initiation factor TFIID subunit 5
    IPR001680 WD40 repeat
    IPR019775 WD40 repeat, conserved site
    IPR017986 WD40-repeat-containing domain
    IPR036322 WD40-repeat-containing domain superfamily
    IPR015943 WD40/YVTN repeat-like-containing domain superfamily
Molecular
Reagents
less
  • All nucleic 11
    cDNA 10
    Primer pair 1

    Microarray probesets 4
Other
Accession IDs
less
MGI:2147674
References
more
  • Summaries
    All 35
    Developmental Gene Expression 7
    Gene Ontology 5
    Phenotypes 4
  • Earliest
    J:25214 LeDouarin B, et al., The N-terminal part of TIF1, a putative mediator of the ligand-dependent activation function (AF-2) of nuclear receptors, is fused to B-raf in the oncogenic protein T18. EMBO J. 1995 May 1;14(9):2020-33
  • Latest
    J:245730 Bardot P, et al., The TAF10-containing TFIID and SAGA transcriptional complexes are dispensable for early somitogenesis in the mouse embryo. Development. 2017 Oct 15;144(20):3808-3818

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory