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Bank1
Gene Detail
Symbol

Name
ID
Bank1
B cell scaffold protein with ankyrin repeats 1
MGI:2442120
Synonyms
A530094C12Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 3
63.04 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr3:136053363-136326066 bp, - strand
From VEGA annotation of GRCm38

  272704 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:9926  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken

HCOP human homology predictions: BANK1
Gene Tree: Bank1

Human
homologs
BANK1, B-cell scaffold protein with ankyrin repeats 1
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 55024
neXtProt AC: NX_Q8NDB2

Human Synonyms: BANK

Human Chr (Location): 4q24; chr4:101790607-102074812 (+)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human BANK1

Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
Incidental mutations (data from Mutagenetix , APF , CvDC )
 
Mice homozygous for a knock-out allele exhibit increased germinal center formation and IgM production in response to T-dependent antigens, and show enhanced CD40-mediated B cell proliferative and survival responses.
 
Interactions
Bank1 interacts with 164 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (8 annotations)
Process B cell activation, negative regulation of B cell activation, ...
Component cellular_component
Function protein binding
External Resources: FuncBase
Expression
cDNA source data(27)
Other mouse links: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(27) cDNA(27)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000052558 (Evidence)
Ensembl Gene Model ENSMUSG00000037922 (Evidence)
Entrez Gene 242248 (Evidence)
UniGene 30832
DFCI TC1581838, TC1709009
DoTS DT.101276270, DT.487891
NIA Mouse Gene Index U024687
Consensus CDS Project CCDS38645.1, CCDS80026.1
International Mouse Phenotyping Consortium Status Bank1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000052558 VEGA Gene Model | MGI Sequence Detail 272704 C57BL/6J ±  kb
transcript OTTMUST00000131761 VEGA | MGI Sequence Detail 3268 Not Applicable 
polypeptide OTTMUSP00000070387 VEGA | MGI Sequence Detail 783 Not Applicable 

For the selected sequences
All sequences(53) RefSeq(12) UniProt(6)
Polymorphisms
SNPs within 2kb(2314 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR020683 Ankyrin repeat-containing domain
InterPro IPR017893 DBB domain
Protein Ontology PR:000004639 B-cell scaffold protein with ankyrin repeats
References
(Earliest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
(Latest) J:207126 Wu YY, et al., BANK1 controls CpG-induced IL-6 secretion via a p38 and MNK1/2/eIF4E translation initiation pathway. J Immunol. 2013 Dec 15;191(12):6110-6
All references(32)
Other
accession IDs
MGI:2139723

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory