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Insyn1 Gene Detail
Summary
  • Symbol
    Insyn1
  • Name
    inhibitory synaptic factor 1
  • Synonyms
    6030419C18Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2442108
    NCBI Gene: 319477
  • Alliance
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:58488603-58499742 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 9, 31.79 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    30 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2442108
protein coding gene Chr9:58488603-58499780 (+)
129S1/SvImJ MGP_129S1SvImJ_G0034891
protein coding gene Chr9:57783717-57795911 (+)
A/J MGP_AJ_G0034872
protein coding gene Chr9:55907888-55918997 (+)
AKR/J MGP_AKRJ_G0034801
protein coding gene Chr9:57205289-57216398 (+)
BALB/cJ MGP_BALBcJ_G0034864
protein coding gene Chr9:55679691-55690805 (+)
C3H/HeJ MGP_C3HHeJ_G0034574
protein coding gene Chr9:57689407-57700494 (+)
C57BL/6NJ MGP_C57BL6NJ_G0035383
protein coding gene Chr9:59395324-59406466 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0032294
protein coding gene Chr9:55180767-55191838 (+)
CAST/EiJ MGP_CASTEiJ_G0033895
protein coding gene Chr9:57781402-57793719 (+)
CBA/J MGP_CBAJ_G0034545
protein coding gene Chr9:61484096-61497199 (+)
DBA/2J MGP_DBA2J_G0034704
protein coding gene Chr9:55758227-55769356 (+)
FVB/NJ MGP_FVBNJ_G0034646
protein coding gene Chr9:55000353-55011462 (+)
LP/J MGP_LPJ_G0034787
protein coding gene Chr9:58064842-58075949 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0034689
protein coding gene Chr9:62923959-62935076 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0035405
protein coding gene Chr9:57216544-57227641 (+)
PWK/PhJ no annotation
SPRET/EiJ MGP_SPRETEiJ_G0033434
protein coding gene Chr9:57504567-57515692 (+)
WSB/EiJ MGP_WSBEiJ_G0034008
protein coding gene Chr9:57171598-57183547 (+)



Homology
more
  • Human Ortholog
    INSYN1, inhibitory synaptic factor 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    INSYN1, inhibitory synaptic factor 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    C15orf59
  • Links
    NCBI Gene ID: 388135
    neXtProt AC: NX_Q2T9L4
    UniProt: Q2T9L4

  • Chr Location
    15q24.1; chr15:73735431-73753170 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 18538
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: INSYN1
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 319477 NCBI Gene Model | MGI Sequence Detail 11140 C57BL/6J ±  kb
transcript NM_176921 RefSeq | MGI Sequence Detail 2177 C57BL/6  
polypeptide Q8CD60 UniProt | EBI | MGI Sequence Detail 292 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR027997 Protein Largen/Inhibitory synaptic factor 1
Molecular
Reagents
less
  • All nucleic 6
    Genomic 1
    cDNA 5

    Microarray probesets 2
References
more
  • Summaries
    All 18
    Gene Ontology 2
    Phenotypes 3
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:235653 Uezu A, et al., Identification of an elaborate complex mediating postsynaptic inhibition. Science. 2016 Sep 9;353(6304):1123-9

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
08/06/2019
MGI 6.14
The Jackson Laboratory