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Ppm1h Gene Detail
Summary
  • Symbol
    Ppm1h
  • Name
    protein phosphatase 1H (PP2C domain containing)
  • Synonyms
    A430075L18Rik, ARHCL1, C030002B11Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2442087
    NCBI Gene: 319468
Location & Maps
more
  • Sequence Map
    Chr10:122678762-122945795 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      267034 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 10, 70.44 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    PPM1H, protein phosphatase, Mg2+/Mn2+ dependent 1H
  • Vertebrate Orthologs
    10
  • Human Ortholog
    PPM1H, protein phosphatase, Mg2+/Mn2+ dependent 1H
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ARHCL1, NERPP-2C, URCC2
  • Links
    NCBI Gene ID: 57460
    neXtProt AC: NX_Q9ULR3

  • Chr Location
    12q14.1; chr12:62643982-62934885 (-)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 18537
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed
  • HCOP
    human homology predictions: PPM1H
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000032921 VEGA Gene Model | MGI Sequence Detail 267034 C57BL/6J ±  kb
transcript OTTMUST00000082056 VEGA | MGI Sequence Detail 6369 Not Applicable  
polypeptide OTTMUSP00000043963 VEGA | MGI Sequence Detail 513 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    2159 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 15
    cDNA 14
    Other 1

    Microarray probesets 5
Other
Accession IDs
less
MGI:1925790
References
more
  • Summaries
    All 27
    Developmental Gene Expression 2
    Gene Ontology 3
    Phenotypes 2
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:194018 Chida T, et al., N-Myristoylation is essential for protein phosphatases PPM1A and PPM1B to dephosphorylate their physiological substrates in cells. Biochem J. 2013 Feb 1;449(3):741-9

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/13/2016
MGI 6.05
The Jackson Laboratory