About   Help   FAQ
Tmem30b Gene Detail
Summary
  • Symbol
    Tmem30b
  • Name
    transmembrane protein 30B
  • Synonyms
    9130011B11Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2442082
    NCBI Gene: 238257
Location & Maps
more
  • Sequence Map
    Chr12:73543114-73546395 bp, - strand
  • From NCBI annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      3282 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 12, 30.65 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    TMEM30B, transmembrane protein 30B
  • Vertebrate Orthologs
    8
  • Human Ortholog
    TMEM30B, transmembrane protein 30B
    Orthology source: HGNC, HomoloGene
  • Synonyms
    CDC50B
  • Links
    NCBI Gene ID: 161291
    neXtProt AC: NX_Q3MIR4

  • Chr Location
    14q23.1; chr14:61277370-61281812 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    3
  • Chemically induced (other)
    1
  • Targeted
    2
  • Genomic Mutations
    1 involving Tmem30b
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 238257 NCBI Gene Model | MGI Sequence Detail 3282 C57BL/6J ±  kb
transcript NM_178715 RefSeq | MGI Sequence Detail 3282 C57BL/6  
polypeptide Q8BHG3 UniProt | EBI | MGI Sequence Detail 353 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    25 from dbSNP Build 142
Protein
Information
less
  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000016424 cell cycle control protein 50B
  • InterPro Domains
    IPR005045 CDC50/LEM3 family
    IPR030352 Cell cycle control protein 50B
Molecular
Reagents
less
  • All nucleic 56
    cDNA 56

    Microarray probesets 4
References
more
  • Summaries
    All 28
    Developmental Gene Expression 2
    Gene Ontology 3
    Phenotypes 6
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:226028 Lewandowski JP, et al., Spatiotemporal regulation of GLI target genes in the mammalian limb bud. Dev Biol. 2015 Oct 1;406(1):92-103

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
07/12/2016
MGI 6.04
The Jackson Laboratory