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Rassf2
Gene Detail
Symbol

Name
ID
Rassf2
Ras association (RalGDS/AF-6) domain family member 2
MGI:2442060
Synonyms
3830431H01Rik, 9030412M04Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 2
64.14 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr2:131989415-132030258 bp, - strand
From VEGA annotation of GRCm38

  40844 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:22840  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: RASSF2
Gene Tree: Rassf2

Human
homologs
RASSF2, Ras association (RalGDS/AF-6) domain family member 2
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 9770
neXtProt AC: NX_P50749

Human Synonyms: CENP-34, RASFADIN

Human Chr (Location): 20p13; chr20:4780023-4823645 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Targeted(5)
Incidental mutations (data from Mutagenetix , APF , CvDC )
 
Mice homozygous for a knock-out allele exhibit bone defects and hematopoeitic abnormalities.
 
Interactions
Rassf2 interacts with 504 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (17 annotations)
Process bone remodeling, cell cycle, ...
Component cytoplasm, nucleus
Function protein binding
External Resources: FuncBase
Expression
Literature Summary: (4 records)
Data Summary: Results (182)    Tissues (90)    Images (26)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 182
cDNA source data(53)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase rassf2 ; ZFIN rassf2a    NEW 
Molecular
reagents
All nucleic(53) cDNA(53)
Microarray probesets(5)
Other database
links
VEGA Gene Model OTTMUSG00000016204 (Evidence)
Ensembl Gene Model ENSMUSG00000027339 (Evidence)
Entrez Gene 215653 (Evidence)
UniGene 204737
DFCI TC1624647, TC1582943, TC1708356, TC1675335
DoTS DT.101367610, DT.91335888, DT.94172181
NIA Mouse Gene Index U023387
Consensus CDS Project CCDS16768.1
International Mouse Phenotyping Consortium Status Rassf2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000016204 VEGA Gene Model | MGI Sequence Detail 40844 C57BL/6J ±  kb
transcript OTTMUST00000038809 VEGA | MGI Sequence Detail 8233 Not Applicable 
polypeptide OTTMUSP00000017352 VEGA | MGI Sequence Detail 326 Not Applicable 

For the selected sequences
All sequences(58) RefSeq(14) UniProt(3)
Polymorphisms
SNPs within 2kb(416 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000159 Ras-association
InterPro IPR011524 SARAH domain
Protein Ontology PR:000013764 ras association domain-containing protein 2
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:181952 Song H, et al., Ablation of Rassf2 induces bone defects and subsequent haematopoietic anomalies in mice. EMBO J. 2012 Mar 7;31(5):1147-59
All references(32)
Other
accession IDs
MGI:1918753, MGI:2139089, MGI:2139357

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory