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Nipa1 Gene Detail
Summary
  • Symbol
    Nipa1
  • Name
    non imprinted in Prader-Willi/Angelman syndrome 1 homolog (human)
  • Synonyms
    1110027G09Rik, A830014A18Rik, Spg6
  • Feature Type
    protein coding gene
  • IDs
    MGI:2442058
    NCBI Gene: 233280
  • Gene Overview
    MyGene.info: NIPA1
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:55978484-56019573 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 33.42 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    536 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2442058
protein coding gene Chr7:55977567-56019954 (-)
129S1/SvImJ MGP_129S1SvImJ_G0032315
protein coding gene Chr7:56783541-56827661 (-)
A/J MGP_AJ_G0032294
protein coding gene Chr7:55931925-55975424 (-)
AKR/J MGP_AKRJ_G0032230
protein coding gene Chr7:57240329-57281858 (-)
BALB/cJ MGP_BALBcJ_G0032306
protein coding gene Chr7:55542334-55585086 (-)
C3H/HeJ MGP_C3HHeJ_G0032019
protein coding gene Chr7:57576741-57619921 (-)
C57BL/6NJ MGP_C57BL6NJ_G0032799
protein coding gene Chr7:59355587-59399227 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0029806
protein coding gene Chr7:58598951-58640158 (-)
CAST/EiJ MGP_CASTEiJ_G0031348
protein coding gene Chr7:48788630-48836035 (-)
CBA/J MGP_CBAJ_G0031984
protein coding gene Chr7:61403028-61449452 (-)
DBA/2J MGP_DBA2J_G0032141
protein coding gene Chr7:54954883-55003560 (-)
FVB/NJ MGP_FVBNJ_G0032095
protein coding gene Chr7:54903098-54946478 (-)
LP/J MGP_LPJ_G0032222
protein coding gene Chr7:57843781-57889376 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0032132
protein coding gene Chr7:60923920-60967257 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0032816
protein coding gene Chr7:56222516-56266020 (-)
PWK/PhJ MGP_PWKPhJ_G0031068
protein coding gene Chr7:48211616-48254647 (-)
SPRET/EiJ MGP_SPRETEiJ_G0030909
protein coding gene Chr7:44270695-44312321 (-)
WSB/EiJ MGP_WSBEiJ_G0031466
protein coding gene Chr7:56859959-56908545 (-)



Homology
more
  • Human Ortholog
    NIPA1, NIPA magnesium transporter 1
  • Vertebrate Orthologs
    9
  • Human Ortholog
    NIPA1, NIPA magnesium transporter 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    FSP3, SLC57A1, SPG6
  • Links
    NCBI Gene ID: 123606
    neXtProt AC: NX_Q7RTP0
    UniProt: Q7RTP0

  • Chr Location
    15q11.2; chr15:22786225-22829789 (+)  GRCh38.p7

Human Diseases
more
  • Diseases
    1 with human NIPA1 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    5 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 233280 NCBI Gene Model | MGI Sequence Detail 41090 C57BL/6J ±  kb
    transcript NM_153578 RefSeq | MGI Sequence Detail 1912 C57BL/6  
    polypeptide Q8BHK1 UniProt | EBI | MGI Sequence Detail 323 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 6
      cDNA 5
      Other 1

      Microarray probesets 5
    Other
    Accession IDs
    less
    MGI:1915904
    References
    more
    • Summaries
      All 32
      Developmental Gene Expression 1
      Gene Ontology 5
      Phenotypes 5
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:213427 Adissu HA, et al., Histopathology reveals correlative and unique phenotypes in a high-throughput mouse phenotyping screen. Dis Model Mech. 2014 May;7(5):515-24

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
    Citing These Resources
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    last database update
    11/06/2018
    MGI 6.13
    The Jackson Laboratory