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Nipa1
Gene Detail
Symbol

Name
ID
Nipa1
non imprinted in Prader-Willi/Angelman syndrome 1 homolog (human)
MGI:2442058
Synonyms
1110027G09Rik, A830014A18Rik, Spg6
Feature Type
protein coding gene
Genetic Map
Chromosome 7
33.42 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr7:55977567-56019954 bp, - strand
From VEGA annotation of GRCm38

  42388 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:42327  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: NIPA1
Gene Tree: Nipa1

Human
homologs
NIPA1, non imprinted in Prader-Willi/Angelman syndrome 1
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 123606
neXtProt AC: NX_Q7RTP0

Human Synonyms: FSP3, SPG6

Human Chr (Location): 15q11.2; chr15:22786225-22829789 (+)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human NIPA1

Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Targeted(3)
Incidental mutations (data from APF )
Interactions
Nipa1 interacts with 217 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (10 annotations)
Process ion transport, magnesium ion transport, ...
Component early endosome, endosome, ...
Function magnesium ion transmembrane transporter activity
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (22)    Tissues (21)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 22
cDNA source data(4)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase nipa1    NEW 
Molecular
reagents
All nucleic(5) cDNA(4) Other(1)
Microarray probesets(5)
Other database
links
VEGA Gene Model OTTMUSG00000026329 (Evidence)
Ensembl Gene Model ENSMUSG00000047037 (Evidence)
Entrez Gene 233280 (Evidence)
DFCI TC1770147, TC1599549, TC1583621
DoTS DT.101362252, DT.101268186, DT.110979073, DT.91309024, DT.55204963, DT.55159760
NIA Mouse Gene Index U099224, U028617
Consensus CDS Project CCDS21317.1
International Mouse Phenotyping Consortium Status Nipa1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000026329 VEGA Gene Model | MGI Sequence Detail 42388 C57BL/6J ±  kb
transcript OTTMUST00000065116 VEGA | MGI Sequence Detail 3183 Not Applicable 
polypeptide OTTMUSP00000032412 VEGA | MGI Sequence Detail 323 Not Applicable 

For the selected sequences
All sequences(33) RefSeq(2) UniProt(2)
Polymorphisms
SNPs within 2kb(519 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR008521 Magnesium transporter NIPA
Protein Ontology PR:000011217 magnesium transporter NIPA1
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(31)
Other
accession IDs
MGI:1915904

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory