About   Help   FAQ
Gpr157 Gene Detail
Summary
  • Symbol
    Gpr157
  • Name
    G protein-coupled receptor 157
  • Synonyms
    F730108M23Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2442046
    NCBI Gene: 269604
  • Gene Overview
    MyGene.info: GPR157
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:150087503-150105927 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 4, 80.89 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    235 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2442046
protein coding gene Chr4:150087365-150105927 (.)
129S1/SvImJ MGP_129S1SvImJ_G0029149
protein coding gene Chr4:154012467-154032500 (+)
A/J MGP_AJ_G0029114
protein coding gene Chr4:147565582-147584625 (+)
AKR/J MGP_AKRJ_G0029062
protein coding gene Chr4:151621249-151639790 (+)
BALB/cJ MGP_BALBcJ_G0029130
protein coding gene Chr4:148064000-148082839 (+)
C3H/HeJ MGP_C3HHeJ_G0028851
protein coding gene Chr4:152152952-152171492 (+)
C57BL/6NJ MGP_C57BL6NJ_G0029579
protein coding gene Chr4:159562317-159582079 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0026825
protein coding gene Chr4:139972678-139991771 (+)
CAST/EiJ MGP_CASTEiJ_G0028264
protein coding gene Chr4:149405985-149423752 (+)
CBA/J MGP_CBAJ_G0028813
protein coding gene Chr4:164262454-164280793 (+)
DBA/2J MGP_DBA2J_G0028962
protein coding gene Chr4:147659592-147678439 (+)
FVB/NJ MGP_FVBNJ_G0028926
protein coding gene Chr4:146787933-146806540 (+)
LP/J MGP_LPJ_G0029052
protein coding gene Chr4:153942755-153961396 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0028953
protein coding gene Chr4:167430897-167449439 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0029611
protein coding gene Chr4:152117379-152135919 (+)
PWK/PhJ MGP_PWKPhJ_G0027984
protein coding gene Chr4:143681858-143701337 (+)
SPRET/EiJ MGP_SPRETEiJ_G0027818
protein coding gene Chr4:146374751-146395311 (+)
WSB/EiJ MGP_WSBEiJ_G0028344
protein coding gene Chr4:152253810-152273587 (+)



Homology
more
  • Human Ortholog
    GPR157, G protein-coupled receptor 157
  • Vertebrate Orthologs
    9
  • Human Ortholog
    GPR157, G protein-coupled receptor 157
    Orthology source: HGNC, HomoloGene
  • Links
    NCBI Gene ID: 80045
    neXtProt AC: NX_Q5UAW9
    UniProt: Q5UAW9

  • Chr Location
    1p36.22; chr1:9103390-9129170 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 269604 NCBI Gene Model | MGI Sequence Detail 18425 C57BL/6J ±  kb
transcript NM_177366 RefSeq | MGI Sequence Detail 4762 C57BL/6  
polypeptide Q8C206 UniProt | EBI | MGI Sequence Detail 330 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 12
    cDNA 12

    Microarray probesets 1
References
more
  • Summaries
    All 23
    Developmental Gene Expression 2
    Gene Ontology 3
    Phenotypes 5
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:239188 Takeo Y, et al., The G protein-coupled receptor GPR157 regulates neuronal differentiation of radial glial progenitors through the Gq-IP3 pathway. Sci Rep. 2016 May 04;6:25180

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
12/04/2018
MGI 6.13
The Jackson Laboratory