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Serpine3 Gene Detail
Summary
  • Symbol
    Serpine3
  • Name
    serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 3
  • Synonyms
    E130113E03Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2442020
    NCBI Gene: 319433
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:62663667-62692243 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 14, 33.23 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    191 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2442020
protein coding gene Chr14:62663296-62692243 (+)
129S1/SvImJ MGP_129S1SvImJ_G0021448
protein coding gene Chr14:57121604-57151503 (+)
A/J MGP_AJ_G0021407
protein coding gene Chr14:55835752-55864456 (+)
AKR/J MGP_AKRJ_G0021383
protein coding gene Chr14:57835807-57866490 (+)
BALB/cJ MGP_BALBcJ_G0021413
protein coding gene Chr14:55795171-55824037 (+)
C3H/HeJ MGP_C3HHeJ_G0021190
protein coding gene Chr14:57463666-57493384 (+)
C57BL/6NJ MGP_C57BL6NJ_G0021852
protein coding gene Chr14:59865506-59895288 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0019392
protein coding gene Chr14:53801402-53827211 (+)
CAST/EiJ MGP_CASTEiJ_G0020707
protein coding gene Chr14:53896421-53926904 (+)
CBA/J MGP_CBAJ_G0021157
protein coding gene Chr14:61601570-61632460 (+)
DBA/2J MGP_DBA2J_G0021280
protein coding gene Chr14:55505554-55534550 (+)
FVB/NJ MGP_FVBNJ_G0021259
protein coding gene Chr14:54919947-54948751 (+)
LP/J MGP_LPJ_G0021355
protein coding gene Chr14:58161736-58191286 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0021288
protein coding gene Chr14:60907791-60937190 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0021875
protein coding gene Chr14:56980761-57009162 (+)
PWK/PhJ MGP_PWKPhJ_G0020451
protein coding gene Chr14:52184596-52214355 (+)
SPRET/EiJ MGP_SPRETEiJ_G0020284
protein coding gene Chr14:52958305-52987108 (+)
WSB/EiJ MGP_WSBEiJ_G0020760
protein coding gene Chr14:57299437-57328879 (+)



Homology
more
  • Human Ortholog
    SERPINE3, serpin family E member 3
  • Vertebrate Orthologs
    10
  • Human Ortholog
    SERPINE3, serpin family E member 3
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 647174
    neXtProt AC: NX_A8MV23
    UniProt: A8MV23

  • Chr Location
    13q14.3; chr13:51334976-51362391 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000091155 Ensembl Gene Model | MGI Sequence Detail 28577 C57BL/6J ±  kb
transcript ENSMUST00000171692 Ensembl | MGI Sequence Detail 1402 Not Applicable  
polypeptide ENSMUSP00000125769 Ensembl | MGI Sequence Detail 401 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 1
    cDNA 1

    Microarray probesets 1
References
more
  • Summaries
    All 14
    Gene Ontology 1
    Phenotypes 3
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
06/18/2019
MGI 6.14
The Jackson Laboratory