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Prepl
Gene Detail
 Symbol
Name
ID
Prepl
prolyl endopeptidase-like
MGI:2441932
Synonyms 2810457N15Rik, 9530014L06Rik, D030028O16Rik, MGC:7980, mKIAA0436
Feature Type protein coding gene
Genetic Map
Chromosome 17
55.19 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr17:85063477-85090267 bp, - strand
From Ensembl annotation of GRCm38

  26791 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:15481  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Prepl

Human
homologs
Human Homolog PREPL, prolyl endopeptidase-like
NCBI Gene ID 9581
neXtProt AC  NX_Q4J6C6
Human Chr (Location)  2p21; chr2:44317607-44361862 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(8) : Gene trapped(8)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Prepl interacts with 201 markers (Mir15a, Mir17, Mir18, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (11 annotations)
Process proteolysis
Component cytoplasm, cytoskeleton, ...
Function hydrolase activity, peptidase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (140)    Tissues (16)    Images (23)
Theiler Stages: 23
Assay TypeResults
RNA in situ 140
cDNA source data(10)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(10) cDNA(10)
Microarray probesets(6)
Other database
links
Ensembl Gene ModelENSMUSG00000024127 (Evidence)
Entrez Gene213760 (Evidence)
EC3.4.21.-
Consensus CDS ProjectCCDS29005.1, CCDS50202.1
International Mouse Knockout Project StatusPrepl
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000024127 Ensembl Gene Model | MGI Sequence Detail 26791 C57BL/6J ±  kb
transcript ENSMUST00000171795 Ensembl | MGI Sequence Detail 3830 Not Applicable 
polypeptide ENSMUSP00000130967 Ensembl | MGI Sequence Detail 725 Not Applicable 

For the selected sequences
All sequences(41) RefSeq(10) UniProt(3)
Polymorphisms SNPs within 2kb(89 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR023302 Peptidase S9A, oligopeptidase, N-terminal
InterPro IPR002470 Peptidase S9A, prolyl oligopeptidase
InterPro IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain
Protein Ontology PR:000013201 prolyl endopeptidase-like
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:201362 Morawski M, et al., Cellular and ultra structural evidence for cytoskeletal localization of prolyl endopeptidase-like protein in neurons. Neuroscience. 2013 Jul 9;242:128-39
All references(29)
Other
accession IDs
MGI:1914494, MGI:1924646

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/16/2014
MGI 5.19
The Jackson Laboratory