Prepl
Gene Detail

Symbol Name ID

Prepl prolyl endopeptidase-like MGI:2441932

Synonyms

2810457N15Rik, 9530014L06Rik, D030028O16Rik, MGC:7980, mKIAA0436

Feature Type

protein coding gene

Genetic Map

Chromosome 17

55.19 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr17:85063477-85090267 bp, - strand From Ensembl annotation of GRCm38   26791 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:15481  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Prepl

Human homologs

Human Homolog		PREPL, prolyl endopeptidase-like
NCBI Gene ID		9581
neXtProt AC		NX_Q4J6C6
Human Chr (Location)		2p21; chr2:44544746-44589001 (-)  GRCh37.p10

Alleles and phenotypes

All alleles(8) : Gene trapped(8)

Gene Ontology (GO) classifications

All GO classifications: (8 annotations)

Process	proteolysis
Component	cytoplasm
Function	hydrolase activity, peptidase activity, ...

External Resources: FuncBase

Expression

Literature Summary: (2 records)
Data Summary: Results (140)    Tissues (16)    Images (23)
Theiler Stages: 23

Assay Type	Results
RNA in situ	140

cDNA source data(10)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(10) cDNA(10)
Microarray probesets(6)

Other database links

Ensembl Gene Model	ENSMUSG00000024127 (Evidence)
Entrez Gene	213760 (Evidence)
EC	3.4.21.-
Consensus CDS Project	CCDS29005.1, CCDS50202.1
International Mouse Knockout Project Status	Prepl

Sequences

Length	Strain/Species
genomic	ENSMUSG00000024127	Ensembl Gene Model | MGI Sequence Detail	26791	C57BL/6J
transcript	ENSMUST00000171795	Ensembl | MGI Sequence Detail	3830	Not Applicable
polypeptide	ENSMUSP00000130967	Ensembl | MGI Sequence Detail	725	Not Applicable

All sequences(39) RefSeq(8) UniProt(3)

Polymorphisms

SNPs(56 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR004106	Peptidase S9A/B/C, oligopeptidase, N-terminal beta-propeller
InterPro	IPR023302	Peptidase S9A, oligopeptidase, N-terminal
InterPro	IPR002470	Peptidase S9A, prolyl oligopeptidase
InterPro	IPR001375	Peptidase S9, prolyl oligopeptidase, catalytic domain
Protein Ontology	PR:000013201	prolyl endopeptidase-like

References

(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:178316 Ferretti E, et al., A conserved Pbx-Wnt-p63-Irf6 regulatory module controls face morphogenesis by promoting epithelial apoptosis. Dev Cell. 2011 Oct 18;21(4):627-41
All references(30)

Other accession IDs

MGI:1914494, MGI:1924646