About   Help   FAQ
Ghsr
Gene Detail
Symbol

Name
ID
Ghsr
growth hormone secretagogue receptor
MGI:2441906
Synonyms
C530020I22Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 3
10.86 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr3:27371351-27378010 bp, + strand
From VEGA annotation of GRCm38

  6660 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:57161  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: growth hormone secretagogue/motilin receptor
Gene Tree: Ghsr

Human
homologs
Human Homolog   GHSR, growth hormone secretagogue receptor
NCBI Gene ID 2693
neXtProt AC  NX_Q92847
Human Synonyms  GHDP
Human Chr (Location)  3q26.31; chr3:172443291-172448456 (-)  GRCh38.p2
Mutations,
alleles, and
phenotypes
All mutations/alleles(8) : Targeted(8)
Incidental mutations (data from Mutagenetix , APF , CvDC )
 
Homeostasis is disrupted by inactivation of this gene, namely growth hormone release and appetite stimulation.
 
Interactions
Ghsr interacts with 287 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (3 records)
Data Summary: Results (34)    Tissues (19)    Images (9)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 34
cDNA source data(6)
External Resources: Allen Institute   GENSAT   GEO   Expression Atlas
Molecular
reagents
All nucleic(6) cDNA(6)
Microarray probesets(2)
Other database
links
VEGA Gene ModelOTTMUSG00000051188 (Evidence)
Ensembl Gene ModelENSMUSG00000051136 (Evidence)
Entrez Gene208188 (Evidence)
UniGene194721
DFCITC1599334, TC1669087
DoTSDT.91592257
NIA Mouse Gene IndexU003096
Consensus CDS ProjectCCDS17273.1
International Mouse Knockout Project StatusGhsr
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000051188 VEGA Gene Model | MGI Sequence Detail 6660 C57BL/6J ±  kb
transcript OTTMUST00000129643 VEGA | MGI Sequence Detail 4433 Not Applicable 
polypeptide OTTMUSP00000069617 VEGA | MGI Sequence Detail 364 Not Applicable 

For the selected sequences
All sequences(23) RefSeq(2) UniProt(3)
Polymorphisms
SNPs within 2kb(60 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR017452 GPCR, rhodopsin-like, 7TM
InterPro IPR000276 G protein-coupled receptor, rhodopsin-like
InterPro IPR003905 Growth hormone secretagogue receptor type 1
Protein Ontology PR:000001225 growth hormone secretagogue receptor
References
(Earliest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
(Latest) J:219689 Girardet C, et al., Assessing interactions between Ghsr and Mc3r reveals a role for AgRP in the expression of food anticipatory activity in male mice. Endocrinology. 2014 Dec;155(12):4843-55
All references(79)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
05/12/2015
MGI 5.21
The Jackson Laboratory