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Ghsr
Gene Detail
Symbol

Name
ID
Ghsr
growth hormone secretagogue receptor
MGI:2441906
Synonyms
C530020I22Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 3
10.86 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr3:27371351-27378010 bp, + strand
From Ensembl annotation of GRCm38

  6660 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:57161  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: growth hormone secretagogue/motilin receptor
Gene Tree: Ghsr

Human
homologs
Human Homolog GHSR, growth hormone secretagogue receptor
NCBI Gene ID 2693
neXtProt AC  NX_Q92847
Human Chr (Location)  3q26.31; chr3:172443291-172448456 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human GHSR
Mutations,
alleles, and
phenotypes
All mutations/alleles(8) : Targeted(8)
Incidental mutations (data from Mutagenetix , APF )
 
Homeostasis is disrupted by inactivation of this gene, namely growth hormone release and appetite stimulation.
 
Interactions
Ghsr interacts with 288 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (3 records)
Data Summary: Results (34)    Tissues (19)    Images (9)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 34
cDNA source data(6)
External Resources: Allen Institute   GENSAT   GEO   Expression Atlas
Molecular
reagents
All nucleic(6) cDNA(6)
Microarray probesets(2)
Other database
links
Ensembl Gene ModelENSMUSG00000051136 (Evidence)
Entrez Gene208188 (Evidence)
UniGene194721
DFCITC1599334, TC1669087
DoTSDT.91592257
NIA Mouse Gene IndexU003096
Consensus CDS ProjectCCDS17273.1
International Mouse Knockout Project StatusGhsr
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000051136 Ensembl Gene Model | MGI Sequence Detail 6660 C57BL/6J ±  kb
transcript ENSMUST00000057186 Ensembl | MGI Sequence Detail 4433 Not Applicable 
polypeptide ENSMUSP00000061153 Ensembl | MGI Sequence Detail 364 Not Applicable 

For the selected sequences
All sequences(24) RefSeq(4) UniProt(5)
Polymorphisms
SNPs within 2kb(60 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR017452 GPCR, rhodopsin-like, 7TM
InterPro IPR000276 G protein-coupled receptor, rhodopsin-like
InterPro IPR003905 Growth hormone secretagogue receptor type 1
Protein Ontology PR:000001225 growth hormone secretagogue receptor
References
(Earliest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
(Latest) J:215188 Fujimura K, et al., Ghrelin protects against renal damages induced by angiotensin-II via an antioxidative stress mechanism in mice. PLoS One. 2014;9(4):e94373
All references(73)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory