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Lpp
Gene Detail
 Symbol
Name
ID
Lpp
LIM domain containing preferred translocation partner in lipoma
MGI:2441849
Synonyms 9430020K16Rik, B130055L10Rik
Feature Type protein coding gene
Genetic Map
Chromosome 16
16.17 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr16:24393350-24992576 bp, + strand
From Ensembl annotation of GRCm38

  599227 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:4075  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Lpp

Human
homologs
Human Homolog LPP, LIM domain containing preferred translocation partner in lipoma
NCBI Gene ID 4026
neXtProt AC  NX_Q93052
Human Chr (Location)  3q28; chr3:188153310-188890671 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(84) : Gene trapped(82) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
 
Gene disruption results in fertility problems involving females but not males. Migration and survival of MEFs are also abnormal.
 
Interactions
Lpp interacts with 637 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (8 annotations)
Process cell adhesion
Component cell junction, cytoplasm, ...
Function metal ion binding, protein binding, ...
External Resources: FuncBase
Expression
Literature Summary: (5 records)
Data Summary: Results (38)    Tissues (37)    Images (5)
Theiler Stages: 2, 3, 4, 5, 17, 18, 21, 23, 28
Assay TypeResults
RNA in situ 30
RT-PCR 8
cDNA source data(31)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(38) cDNA(37) Primer pair(1)
Microarray probesets(10)
Other database
links
Ensembl Gene ModelENSMUSG00000033306 (Evidence)
Entrez Gene210126 (Evidence)
DFCITC1574050, TC1586810, TC1588159, TC1589531, TC1591915, TC1602664, TC1606897, TC1610816, TC1620671, TC1623221, TC1623704, TC1641479, TC1652359
NIA Mouse Gene IndexU016966, U149649
Consensus CDS ProjectCCDS28083.1, CCDS49807.1
International Mouse Knockout Project StatusLpp
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000033306 Ensembl Gene Model | MGI Sequence Detail 599227 C57BL/6J ±  kb
transcript ENSMUST00000078988 Ensembl | MGI Sequence Detail 15440 Not Applicable 
polypeptide ENSMUSP00000078005 Ensembl | MGI Sequence Detail 613 Not Applicable 

For the selected sequences
All sequences(79) RefSeq(8) UniProt(2)
Polymorphisms SNPs within 2kb(3332 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001781 Zinc finger, LIM-type
Protein Ontology PR:000009902 lipoma-preferred partner
References (Earliest) J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-le-grand). 1999 Jul;45(5):737-50
(Latest) J:182886 Moik DV, et al., Loss of migfilin expression has no overt consequences on murine development and homeostasis. J Cell Sci. 2011 Feb 1;124(Pt 3):414-21
All references(44)
Other
accession IDs
MGI:2146367, MGI:2146570, MGI:2146704

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory