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Serinc4 Gene Detail
Summary
  • Symbol
    Serinc4
  • Name
    serine incorporator 4
  • Synonyms
    A930015D22Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2441842
    NCBI Gene: 574418
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:121281658-121287245 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 60.39 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    42 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2441842
 protein coding gene Chr2:121269540-121287262 (-)
129S1/SvImJ MGP_129S1SvImJ_G0026393
 protein coding gene Chr2:124341991-124359696 (-)
A/J MGP_AJ_G0026354
 protein coding gene Chr2:119257128-119274908 (-)
AKR/J MGP_AKRJ_G0026333
 protein coding gene Chr2:122603143-122620758 (-)
BALB/cJ MGP_BALBcJ_G0026367
 protein coding gene Chr2:119486885-119504975 (-)
C3H/HeJ MGP_C3HHeJ_G0026113
 protein coding gene Chr2:123082919-123101160 (-)
C57BL/6NJ MGP_C57BL6NJ_G0026814
 protein coding gene Chr2:128411156-128430750 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0024194
 protein coding gene Chr2:114297739-114315704 (-)
CAST/EiJ MGP_CASTEiJ_G0025575
 protein coding gene Chr2:123409169-123429536 (-)
CBA/J MGP_CBAJ_G0026089
 protein coding gene Chr2:132880834-132901876 (-)
DBA/2J MGP_DBA2J_G0026228
 protein coding gene Chr2:118655721-118688825 (-)
FVB/NJ MGP_FVBNJ_G0026190
 protein coding gene Chr2:117475163-117493091 (-)
LP/J MGP_LPJ_G0026329
 protein coding gene Chr2:124588474-124607911 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0026209
 protein coding gene Chr2:137158940-137180420 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0026869
 protein coding gene Chr2:122713679-122731399 (-)
PWK/PhJ MGP_PWKPhJ_G0025311
 protein coding gene Chr2:118262108-118280500 (-)
SPRET/EiJ MGP_SPRETEiJ_G0025110
 protein coding gene Chr2:121920322-121938911 (-)
WSB/EiJ MGP_WSBEiJ_G0025644
 protein coding gene Chr2:123541375-123570128 (-)



Homology
more
  • Human Ortholog
    SERINC4, serine incorporator 4
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SERINC4, serine incorporator 4
  • Links
    NCBI Gene ID: 619189
    neXtProt AC: NX_A6NH21
    UniProt: A6NH21

  • Chr Location
    15q15.3; chr15:43794162-43800220 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
  • All Mutations and Alleles
    7
  • Chemically induced (other)
    1
  • Gene trapped
    3
  • Radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    2 involving Serinc4
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
    27 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    13
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 574418 NCBI Gene Model | MGI Sequence Detail 5588 C57BL/6J ±  kb
transcript NM_001025371 RefSeq | MGI Sequence Detail 2570 Not Specified  
polypeptide Q5XK03 UniProt | EBI | MGI Sequence Detail 492 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 13
    cDNA 13

    Microarray probesets 2
References
more
  • Summaries
    All 24
    Gene Ontology 2
    Phenotypes 7
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory