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Adgrb3 Gene Detail
Summary
  • Symbol
    Adgrb3
  • Name
    adhesion G protein-coupled receptor B3
  • Synonyms
    A830096D10Rik, Bai3
  • Feature Type
    protein coding gene
  • IDs
    MGI:2441837
    NCBI Gene: 210933
Location & Maps
more
  • Sequence Map
    Chr1:25067476-25829707 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      762232 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    ADGRB3, adhesion G protein-coupled receptor B3
  • Vertebrate Orthologs
    10
  • Human Ortholog
    ADGRB3, adhesion G protein-coupled receptor B3
    Orthology source: HGNC, HomoloGene
  • Synonyms
    BAI3
  • Links
    NCBI Gene ID: 577
    neXtProt AC: NX_O60242

  • Chr Location
    6q12; chr6:68635282-69389511 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    4 phenotype references
  • All Mutations and Alleles
    3
  • Chemically induced (other)
    1
  • Gene trapped
    2
  • Genomic Mutations
    1 involving Adgrb3
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000025352 VEGA Gene Model | MGI Sequence Detail 762232 C57BL/6J ±  kb
transcript OTTMUST00000062607 VEGA | MGI Sequence Detail 5432 Not Applicable  
polypeptide OTTMUSP00000030892 VEGA | MGI Sequence Detail 1522 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    5775 from dbSNP Build 137
Protein
Information
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  • UniProt
    7 Sequences
  • Protein Ontology
    PR:000004631 brain-specific angiogenesis inhibitor 3
  • InterPro Domains
    IPR032471 GAIN domain, N-terminal
    IPR008077 GPCR, family 2, brain-specific angiogenesis inhibitor
    IPR001879 GPCR, family 2, extracellular hormone receptor domain
    IPR017981 GPCR, family 2-like
    IPR000832 GPCR, family 2, secretin-like
    IPR017983 GPCR, family 2, secretin-like, conserved site
    IPR000203 GPS motif
    IPR000884 Thrombospondin type-1 (TSP1) repeat
Molecular
Reagents
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  • All nucleic 37
    cDNA 34
    Primer pair 3

    Microarray probesets 1
References
more
  • Summaries
    All 28
    Developmental Gene Expression 4
    Gene Ontology 6
    Phenotypes 4
  • Earliest
    J:77162 Kee HJ, et al., Expression of brain-specific angiogenesis inhibitor 2 (BAI2) in normal and ischemic brain: involvement of BAI2 in the ischemia-induced brain angiogenesis. J Cereb Blood Flow Metab. 2002 Sep;22(9):1054-67
  • Latest
    J:218304 Hamann J, et al., International Union of Basic and Clinical Pharmacology. XCIV. Adhesion G Protein-Coupled Receptors. Pharmacol Rev. 2015 Apr;67(2):338-67

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
02/02/2016
MGI 6.02
The Jackson Laboratory