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Lgr6
Gene Detail
 Symbol
Name
ID
Lgr6
leucine-rich repeat-containing G protein-coupled receptor 6
MGI:2441805
Synonyms A530037C04Rik
Feature Type protein coding gene
Genetic Map
Chromosome 1
58.24 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr1:134986348-135105276 bp, - strand
From VEGA annotation of GRCm38

  118929 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:49680  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: leucine-rich repeat-containing G protein-coupled receptor 4/5/6
Gene Tree: Lgr6

Human
homologs
Human Homolog LGR6, leucine-rich repeat containing G protein-coupled receptor 6
NCBI Gene ID 59352
neXtProt AC  NX_Q9HBX8
Human Synonyms  GPCR, VTS20631
Human Chr (Location)  1q32.1; chr1:202193810-202319761 (+)  GRCh38
Alleles
and
phenotypes
All alleles(4) : Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a reporter/null allele are viable and fertile with no apparent abnormal phenotype. Similarly, mice homozygous for a knock-in allele are healthy and fertile.
 
Gene Ontology
(GO)
classifications
All GO classifications: (15 annotations)
Process G-protein coupled receptor signaling pathway, positive regulation of cell migration, ...
Component integral component of membrane, membrane, ...
Function G-protein coupled receptor activity, protein-hormone receptor activity, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
cDNA source data(18)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(19) Genomic(1) cDNA(18)
Microarray probesets(2)
Other database
links
VEGA Gene ModelOTTMUSG00000026806 (Evidence)
Ensembl Gene ModelENSMUSG00000042793 (Evidence)
Entrez Gene329252 (Evidence)
UniGene279594
DFCITC1583880, TC1598991
DoTSDT.55167088, DT.87068058
NIA Mouse Gene IndexU021790
Consensus CDS ProjectCCDS15314.1
International Mouse Knockout Project StatusLgr6
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000026806 VEGA Gene Model | MGI Sequence Detail 118929 C57BL/6J ±  kb
transcript OTTMUST00000066294 VEGA | MGI Sequence Detail 3628 Not Applicable 
polypeptide OTTMUSP00000033204 VEGA | MGI Sequence Detail 967 Not Applicable 

For the selected sequences
All sequences(35) RefSeq(6) UniProt(2)
Polymorphisms SNPs within 2kb(1447 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR002131 Glycoprotein hormone receptor
InterPro IPR017452 GPCR, rhodopsin-like, 7TM
InterPro IPR000276 G protein-coupled receptor, rhodopsin-like
InterPro IPR001611 Leucine-rich repeat
InterPro IPR000372 Leucine-rich repeat-containing N-terminal
InterPro IPR003591 Leucine-rich repeat, typical subtype
Protein Ontology PR:000001593 leucine-rich repeat-containing G-protein coupled receptor 6
References (Earliest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
(Latest) J:208368 White AC, et al., Stem cell quiescence acts as a tumour suppressor in squamous tumours. Nat Cell Biol. 2014 Jan;16(1):99-107
All references(33)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory