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Shfl Gene Detail
Summary
  • Symbol
    Shfl
  • Name
    shiftless antiviral inhibitor of ribosomal frameshifting
  • Synonyms
    A230050P20Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2441788
    NCBI Gene: 319278
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:20868642-20874307 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 9, 7.65 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    19 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2441788
protein coding gene Chr9:20868605-20874307 (+)
129S1/SvImJ MGP_129S1SvImJ_G0034428
protein coding gene Chr9:18037815-18043458 (+)
A/J MGP_AJ_G0034406
protein coding gene Chr9:17742013-17747678 (+)
AKR/J MGP_AKRJ_G0034333
protein coding gene Chr9:18058688-18064345 (+)
BALB/cJ MGP_BALBcJ_G0034397
protein coding gene Chr9:17637607-17643252 (+)
C3H/HeJ MGP_C3HHeJ_G0034109
protein coding gene Chr9:18374752-18380413 (+)
C57BL/6NJ MGP_C57BL6NJ_G0034918
protein coding gene Chr9:18754232-18759873 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0031848
protein coding gene Chr9:16870935-16876838 (+)
CAST/EiJ MGP_CASTEiJ_G0033432
protein coding gene Chr9:18196453-18202117 (+)
CBA/J MGP_CBAJ_G0034082
protein coding gene Chr9:19477873-19483541 (+)
DBA/2J MGP_DBA2J_G0034241
protein coding gene Chr9:17730563-17736216 (+)
FVB/NJ MGP_FVBNJ_G0034184
protein coding gene Chr9:17232051-17237704 (+)
LP/J MGP_LPJ_G0034326
protein coding gene Chr9:18215408-18221061 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0034227
protein coding gene Chr9:21100915-21106500 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0034938
protein coding gene Chr9:18013072-18018721 (+)
PWK/PhJ MGP_PWKPhJ_G0033138
protein coding gene Chr9:17696423-17702100 (+)
SPRET/EiJ MGP_SPRETEiJ_G0032972
protein coding gene Chr9:18064322-18069951 (+)
WSB/EiJ MGP_WSBEiJ_G0033547
protein coding gene Chr9:17745256-17750895 (+)



Homology
more
  • Human Ortholog
    SHFL, shiftless antiviral inhibitor of ribosomal frameshifting
  • Vertebrate Orthologs
    8
  • Human Ortholog
    SHFL, shiftless antiviral inhibitor of ribosomal frameshifting
    Orthology source: HomoloGene, HGNC
  • Synonyms
    C19orf66, IRAV, RyDEN, SFL
  • Links
    NCBI Gene ID: 55337
    neXtProt AC: NX_Q9NUL5
    UniProt: Q9NUL5

  • Chr Location
    19p13.2; chr19:10086119-10093252 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000038884 Ensembl Gene Model | MGI Sequence Detail 5666 C57BL/6J ±  kb
transcript ENSMUST00000043911 Ensembl | MGI Sequence Detail 1683 Not Applicable  
polypeptide ENSMUSP00000045384 Ensembl | MGI Sequence Detail 290 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR026795 Repressor of yield of DENV protein
Molecular
Reagents
less
  • All nucleic 23
    cDNA 23

    Microarray probesets 2
References
more
  • Summaries
    All 24
    Developmental Gene Expression 1
    Gene Ontology 1
    Phenotypes 6
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:164377 Pereira JD, et al., Ezh2, the histone methyltransferase of PRC2, regulates the balance between self-renewal and differentiation in the cerebral cortex. Proc Natl Acad Sci U S A. 2010 Sep 7;107(36):15957-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
09/05/2019
MGI 6.14
The Jackson Laboratory