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Washc4 Gene Detail
Summary
  • Symbol
    Washc4
  • Name
    WASH complex subunit 4
  • Synonyms
    A230046K03Rik, mKIAA1033
  • Feature Type
    protein coding gene
  • IDs
    MGI:2441787
    NCBI Gene: 319277
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:83543941-83596473 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 10, 41.29 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    191 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2441787
protein coding gene Chr10:83543752-83596473 (.)
129S1/SvImJ MGP_129S1SvImJ_G0017587
protein coding gene Chr10:84354809-84407119 (+)
A/J MGP_AJ_G0017567
protein coding gene Chr10:81504445-81557519 (+)
AKR/J MGP_AKRJ_G0017526
protein coding gene Chr10:83757765-83809958 (+)
BALB/cJ MGP_BALBcJ_G0017530
protein coding gene Chr10:81755529-81811220 (+)
C3H/HeJ MGP_C3HHeJ_G0017352
protein coding gene Chr10:83852200-83906238 (+)
C57BL/6NJ MGP_C57BL6NJ_G0017987
protein coding gene Chr10:87258385-87314572 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0015671
protein coding gene Chr10:77203046-77255040 (+)
CAST/EiJ MGP_CASTEiJ_G0016919
protein coding gene Chr10:83726672-83782174 (+)
CBA/J MGP_CBAJ_G0017322
protein coding gene Chr10:90878111-90936226 (+)
DBA/2J MGP_DBA2J_G0017428
protein coding gene Chr10:80656401-80708936 (+)
FVB/NJ MGP_FVBNJ_G0017422
protein coding gene Chr10:79894741-79947688 (+)
LP/J MGP_LPJ_G0017500
protein coding gene Chr10:84997068-85052284 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0017450
protein coding gene Chr10:92537623-92595031 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0018024
protein coding gene Chr10:83694143-83746882 (+)
PWK/PhJ MGP_PWKPhJ_G0016700
protein coding gene Chr10:80524404-80577422 (+)
SPRET/EiJ MGP_SPRETEiJ_G0016490
protein coding gene Chr10:82299490-82353054 (+)
WSB/EiJ MGP_WSBEiJ_G0016978
protein coding gene Chr10:83708877-83763378 (+)



Homology
more
  • Human Ortholog
    WASHC4, WASH complex subunit 4
  • Vertebrate Orthologs
    11
  • Human Ortholog
    WASHC4, WASH complex subunit 4
    Orthology source: HGNC, HomoloGene
  • Synonyms
    KIAA1033, MRT43, SWIP
  • Links
    NCBI Gene ID: 23325
    neXtProt AC: NX_Q2M389
    UniProt: Q2M389

  • Chr Location
    12q23.3; chr12:105107714-105169134 (+)  GRCh38.p7

Human Diseases
more
  • Diseases
    1 with human WASHC4 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 319277 NCBI Gene Model | MGI Sequence Detail 52533 C57BL/6J ±  kb
transcript NM_001033375 RefSeq | MGI Sequence Detail 5863 C57BL/6  
polypeptide Q3UMB9 UniProt | EBI | MGI Sequence Detail 1173 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR027307 WASH complex subunit 7
    IPR028282 WASH complex subunit 7, central domain
    IPR028283 WASH complex subunit 7, C-terminal
    IPR028191 WASH complex subunit 7, N-terminal
Molecular
Reagents
less
  • All nucleic 16
    cDNA 16

    Microarray probesets 6
Other
Accession IDs
less
MGI:2143496
References
more
  • Summaries
    All 40
    Developmental Gene Expression 1
    Gene Ontology 7
    Phenotypes 10
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/04/2018
MGI 6.13
The Jackson Laboratory