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Gpr26 Gene Detail
Summary
  • Symbol
    Gpr26
  • Name
    G protein-coupled receptor 26
  • Synonyms
    9630036A11Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2441758
    NCBI Gene: 233919
  • Gene Overview
    MyGene.info: GPR26
  • Alliance
Location & Maps
more
  • Sequence Map
    Chr7:131966460-131994405 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      27946 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 75.28 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    GPR26, G protein-coupled receptor 26
  • Vertebrate Orthologs
    9
  • Human Ortholog
    GPR26, G protein-coupled receptor 26
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 2849
    neXtProt AC: NX_Q8NDV2
    UniProt: Q8NDV2

  • Chr Location
    10q26.13; chr10:123666355-123697399 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    19 phenotypes from 2 alleles in 2 genetic backgrounds
    5 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for one null allele exhibit increased anxiety- and depression-related behaviors and alcohol preference. Female mice homozygous for another allele display increased susceptibility to diet-induced obesity with increased food intake.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic OTTMUSG00000023040 VEGA Gene Model | MGI Sequence Detail 27946 C57BL/6J ±  kb
    transcript OTTMUST00000055518 VEGA | MGI Sequence Detail 11571 Not Applicable  
    polypeptide OTTMUSP00000026593 VEGA | MGI Sequence Detail 337 Not Applicable  
    For the selected sequence
    Polymorphisms
    less
    • SNPs within 2kb
      76 from dbSNP Build 142
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 17
      cDNA 15
      Primer pair 2

      Microarray probesets 3
    References
    more
    • Summaries
      All 33
      Developmental Gene Expression 7
      Gene Ontology 4
      Phenotypes 5
    • Earliest
      J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
    • Latest
      J:241394 Mattiske T, et al., Embryonic forebrain transcriptome of mice with polyalanine expansion mutations in the ARX homeobox gene. Hum Mol Genet. 2016 Dec 15;25(24):5433-5443

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
    Citing These Resources
    Funding Information
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    last database update
    07/31/2018
    MGI 6.12
    The Jackson Laboratory