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Npsr1
Gene Detail
Symbol

Name
ID
Npsr1
neuropeptide S receptor 1
MGI:2441738
Synonyms
9330128H10Rik, Gpr154, PGR14, VRR1
Feature Type
protein coding gene
Genetic Map
Chromosome 9
9.99 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr9:24097996-24316398 bp, + strand
From VEGA annotation of GRCm38

  218403 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:45515  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog

Protein SuperFamily: neuropeptide S receptor
Gene Tree: Npsr1

Human
homologs
Human Homolog NPSR1, neuropeptide S receptor 1
NCBI Gene ID 387129
neXtProt AC  NX_Q6W5P4
Human Synonyms  ASRT2, GPR154, GPRA, NPSR, PGR14, VRR1
Human Chr (Location)  7p14.3; chr7:34658285-34878332 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human NPSR1
Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Gene trapped(1) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a knock-out allele exhibit decreased airway resistance when treated with high concentrations of U-46619.
 
Interactions
Npsr1 interacts with 310 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
Expression
cDNA source data(7)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(9) cDNA(7) Other(2)
Microarray probesets(1)
Other database
links
VEGA Gene ModelOTTMUSG00000024228 (Evidence)
Ensembl Gene ModelENSMUSG00000043659 (Evidence)
Entrez Gene319239 (Evidence)
UniGene130824
DFCITC1589877, TC1621626
DoTSDT.94128957, DT.101712788
NIA Mouse Gene IndexU010172
Consensus CDS ProjectCCDS22930.1
International Mouse Knockout Project StatusNpsr1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000024228 VEGA Gene Model | MGI Sequence Detail 218403 C57BL/6J ±  kb
transcript OTTMUST00000059289 VEGA | MGI Sequence Detail 3791 Not Applicable 
polypeptide OTTMUSP00000028831 VEGA | MGI Sequence Detail 371 Not Applicable 

For the selected sequences
All sequences(48) RefSeq(12) UniProt(7)
Polymorphisms
SNPs within 2kb(1289 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR017452 GPCR, rhodopsin-like, 7TM
InterPro IPR000276 G protein-coupled receptor, rhodopsin-like
InterPro IPR027294 Neuropeptide S receptor
InterPro IPR001817 Vasopressin receptor
Protein Ontology PR:000001491 neuropeptide S receptor
References
(Earliest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
(Latest) J:207647 Pulga A, et al., Anxiolytic- and panicolytic-like effects of Neuropeptide S in the mouse elevated T-maze. Eur J Neurosci. 2012 Dec;36(11):3531-7
All references(31)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/11/2014
MGI 5.20
The Jackson Laboratory