About   Help   FAQ
Trim12c
Gene Detail
 Symbol
Name
ID
Trim12c
tripartite motif-containing 12C
MGI:4821183
Synonyms 9230105E10Rik, Trim12-2
Feature Type protein coding gene
Genetic Map
Chromosome 7
55.69 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr7:104338754-104353362 bp, - strand
From VEGA annotation of GRCm38

  14609 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:75345  Vertebrate Homology Class
1 human; 2 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 2 cattle

Protein SuperFamily: tripartite motif-containing protein
Gene Tree: Trim12c

Human
homologs
Human Homolog TRIM5, tripartite motif containing 5
NCBI Gene ID 85363
neXtProt AC  NX_Q9C035
Human Synonyms  RNF88, TRIM5alpha
Human Chr (Location)  11p15; chr11:5663195-5685109 (-)  GRCh38
Mutations,
alleles, and
phenotypes
Incidental mutations (data from Mutagenetix , APF )
Interactions
Trim12c interacts with 280 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (11 annotations)
Process pattern recognition receptor signaling pathway, protein ubiquitination
Component cytoplasm, cytoplasmic mRNA processing body, ...
Function identical protein binding, metal ion binding, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (23)    Tissues (14)    Images (2)
Theiler Stages: 23
Assay TypeResults
RNA in situ 23
cDNA source data(32)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(32) cDNA(32)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000019193 (Evidence)
Ensembl Gene ModelENSMUSG00000057143 (Evidence)
Entrez Gene319236 (Evidence)
UniGene425502
Consensus CDS ProjectCCDS52344.1
International Mouse Knockout Project StatusTrim12c
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000019193 VEGA Gene Model | MGI Sequence Detail 14609 C57BL/6J ±  kb
transcript OTTMUST00000045997 VEGA | MGI Sequence Detail 3740 Not Applicable 
polypeptide OTTMUSP00000020743 VEGA | MGI Sequence Detail 497 Not Applicable 

For the selected sequences
All sequences(27) RefSeq(4) UniProt(5)
Polymorphisms SNPs within 2kb(193 from dbSNP Build 137)    SNPs within 2kb including multiple locations(253)
Protein-related
information
ResourceIDDescription
InterPro IPR001870 B30.2/SPRY domain
InterPro IPR003879 Butyrophylin-like
InterPro IPR008985 Concanavalin A-like lectin/glucanases superfamily
InterPro IPR003877 SPla/RYanodine receptor SPRY
InterPro IPR000315 Zinc finger, B-box
InterPro IPR013083 Zinc finger, RING/FYVE/PHD-type
InterPro IPR001841 Zinc finger, RING-type
InterPro IPR017907 Zinc finger, RING-type, conserved site
References (Earliest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
(Latest) J:162981 Tareen SU, et al., An expanded clade of rodent Trim5 genes. Virology. 2009 Mar 15;385(2):473-83
All references(17)
Other
accession IDs
MGI:2441735

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
08/12/2014
MGI 5.19
The Jackson Laboratory