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Abcc12 Gene Detail
Summary
  • Symbol
    Abcc12
  • Name
    ATP-binding cassette, sub-family C (CFTR/MRP), member 12
  • Synonyms
    4930467B22Rik, MRP9
  • Feature Type
    protein coding gene
  • IDs
    MGI:2441679
    NCBI Gene: 244562
  • Gene Overview
    MyGene.info: ABCC12
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:86504576-86580688 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 8, 42.06 cM, cytoband D3
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    432 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2441679
protein coding gene Chr8:86482260-86580688 (-)
129S1/SvImJ MGP_129S1SvImJ_G0033907
protein coding gene Chr8:87450061-87548667 (-)
A/J MGP_AJ_G0033890
protein coding gene Chr8:84020097-84117342 (-)
AKR/J MGP_AKRJ_G0033816
protein coding gene Chr8:86505359-86606612 (-)
BALB/cJ MGP_BALBcJ_G0033883
protein coding gene Chr8:84167275-84263595 (-)
C3H/HeJ MGP_C3HHeJ_G0033594
protein coding gene Chr8:87114642-87213227 (-)
C57BL/6NJ MGP_C57BL6NJ_G0034404
protein coding gene Chr8:90812714-90913643 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0031344
protein coding gene Chr8:78059135-78149293 (-)
CAST/EiJ MGP_CASTEiJ_G0032924
protein coding gene Chr8:86520954-86621582 (-)
CBA/J MGP_CBAJ_G0033569
protein coding gene Chr8:93886623-93989691 (-)
DBA/2J MGP_DBA2J_G0033722
protein coding gene Chr8:83631906-83728041 (-)
FVB/NJ MGP_FVBNJ_G0033670
protein coding gene Chr8:82582167-82675223 (-)
LP/J MGP_LPJ_G0033814
protein coding gene Chr8:87571726-87675710 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0033713
protein coding gene Chr8:96421303-96522950 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0034421
protein coding gene Chr8:86492483-86587714 (-)
PWK/PhJ MGP_PWKPhJ_G0032628
protein coding gene Chr8:82873863-82969531 (-)
SPRET/EiJ MGP_SPRETEiJ_G0032463
protein coding gene Chr8:85255162-85349162 (-)
WSB/EiJ MGP_WSBEiJ_G0033036
protein coding gene Chr8:86924518-87022426 (-)



Homology
more
  • Human Ortholog
    ABCC12, ATP binding cassette subfamily C member 12
  • Vertebrate Orthologs
    8
  • Human Ortholog
    ABCC12, ATP binding cassette subfamily C member 12
    Orthology source: HomoloGene, HGNC
  • Synonyms
    MRP9
  • Links
    NCBI Gene ID: 94160
    neXtProt AC: NX_Q96J65
    UniProt: Q96J65

  • Chr Location
    16q12.1; chr16:48082973-48146770 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    29 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 244562 NCBI Gene Model | MGI Sequence Detail 76113 C57BL/6J ±  kb
transcript NM_172912 RefSeq | MGI Sequence Detail 4511 C57BL/6  
polypeptide Q80WJ6 UniProt | EBI | MGI Sequence Detail 1366 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000003557 multidrug resistance-associated protein 9
  • InterPro Domains
    IPR003593 AAA+ ATPase domain
    IPR017871 ABC transporter, conserved site
    IPR003439 ABC transporter-like
    IPR011527 ABC transporter type 1, transmembrane domain
    IPR036640 ABC transporter type 1, transmembrane domain superfamily
    IPR030250 Multidrug resistance-associated protein 9
    IPR027417 P-loop containing nucleoside triphosphate hydrolase
Molecular
Reagents
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  • All nucleic 21
    cDNA 18
    Primer pair 2
    Other 1

    Microarray probesets 3
References
more
  • Summaries
    All 56
    Developmental Gene Expression 2
    Gene Ontology 5
    Phenotypes 29
  • Earliest
    J:13049 Gruneberg H, Genetical studies on the skeleton of the mouse. XVIII. Three genes for syndactylism. J Genet. 1956;54:113-145
  • Latest
    J:266142 Grosjean F, et al., Pharmacologic control of oxidative stress and inflammation determines whether diabetic glomerulosclerosis progresses or decreases: A pilot study in sclerosis-prone mice. PLoS One. 2018;13(9):e0204366

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory