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Mrgprb2
Gene Detail
Symbol

Name
ID
Mrgprb2
MAS-related GPR, member B2
MGI:2441674
Synonyms
4833406I20Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 7
31.11 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr7:48550965-48558086 bp, - strand
From VEGA annotation of GRCm38

  7122 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:86246  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque

HCOP human homology predictions: MRGPRX1
Protein SuperFamily: mas-related G protein-coupled receptor
Gene Tree: Mrgprb2

Human
homologs
MRGPRX1, MAS-related GPR, member X1
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 259249
neXtProt AC: NX_Q96LB2

Human Synonyms: GPCR, MGRG2, MRGX1, SNSR4

Human Chr (Location): 11p15.1,11; chr11:18933813-18935002 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
Incidental mutations (data from Mutagenetix , APF )
Interactions
Mrgprb2 interacts with 137 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
Expression
cDNA source data(7)
Other mouse links: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(7) cDNA(7)
Microarray probesets(2)
Other database
links
VEGA Gene Model OTTMUSG00000046627 (Evidence)
Ensembl Gene Model ENSMUSG00000050425 (Evidence)
Entrez Gene 243979 (Evidence)
UniGene 83689
DFCI TC1587578
DoTS DT.40155046
NIA Mouse Gene Index U042809
Consensus CDS Project CCDS21303.1
International Mouse Phenotyping Consortium Status Mrgprb2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000046627 VEGA Gene Model | MGI Sequence Detail 7122 C57BL/6J ±  kb
transcript OTTMUST00000121204 VEGA | MGI Sequence Detail 2077 Not Applicable 
polypeptide OTTMUSP00000066876 VEGA | MGI Sequence Detail 338 Not Applicable 

For the selected sequences
All sequences(22) RefSeq(4) UniProt(2)
Polymorphisms
SNPs within 2kb(77 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR017452 GPCR, rhodopsin-like, 7TM
InterPro IPR000276 G protein-coupled receptor, rhodopsin-like
InterPro IPR026234 Mas-related G protein-coupled receptor family
Protein Ontology PR:000001697 mas-related G-protein coupled receptor B2
References
(Earliest) J:71586 Dong X, et al., A diverse family of GPCRs expressed in specific subsets of nociceptive sensory neurons. Cell. 2001 Sep 7;106(5):619-32
(Latest) J:219209 McNeil BD, et al., Identification of a mast-cell-specific receptor crucial for pseudo-allergic drug reactions. Nature. 2015 Mar 12;519(7542):237-41
All references(23)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/30/2015
MGI 5.22
The Jackson Laboratory