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Mrgprb2
Gene Detail
 Symbol
Name
ID
Mrgprb2
MAS-related GPR, member B2
MGI:2441674
Synonyms 4833406I20Rik
Feature Type protein coding gene
Genetic Map
Chromosome 7
31.11 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr7:48550965-48558086 bp, - strand
From VEGA annotation of GRCm38

  7122 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:86246  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque

Protein SuperFamily: mas-related G protein-coupled receptor
Gene Tree: Mrgprb2

Human
homologs
Human Homolog MRGPRX1, MAS-related GPR, member X1
NCBI Gene ID 259249
neXtProt AC  NX_Q96LB2
Human Synonyms  GPCR, MGRG2, MRGX1, SNSR4
Human Chr (Location)  11p15.1|11; chr11:18933813-18935002 (-)  GRCh38
Mutations,
alleles, and
phenotypes
Incidental mutations (data from Mutagenetix , APF )
Interactions
Mrgprb2 interacts with 137 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (9 annotations)
Process G-protein coupled receptor signaling pathway, signal transduction
Component integral component of membrane, membrane
Function G-protein coupled receptor activity, signal transducer activity
External Resources: FuncBase
Expression
cDNA source data(7)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(7) cDNA(7)
Microarray probesets(2)
Other database
links
VEGA Gene ModelOTTMUSG00000046627 (Evidence)
Ensembl Gene ModelENSMUSG00000050425 (Evidence)
Entrez Gene243979 (Evidence)
UniGene83689
DFCITC1587578
DoTSDT.40155046
NIA Mouse Gene IndexU042809
Consensus CDS ProjectCCDS21303.1
International Mouse Knockout Project StatusMrgprb2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000046627 VEGA Gene Model | MGI Sequence Detail 7122 C57BL/6J ±  kb
transcript OTTMUST00000121204 VEGA | MGI Sequence Detail 2077 Not Applicable 
polypeptide OTTMUSP00000066876 VEGA | MGI Sequence Detail 338 Not Applicable 

For the selected sequences
All sequences(22) RefSeq(4) UniProt(2)
Polymorphisms SNPs within 2kb(77 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR017452 GPCR, rhodopsin-like, 7TM
InterPro IPR000276 G protein-coupled receptor, rhodopsin-like
InterPro IPR026234 Mas-related G protein-coupled receptor family
Protein Ontology PR:000001697 mas-related G-protein coupled receptor B2
References (Earliest) J:71586 Dong X, et al., A diverse family of GPCRs expressed in specific subsets of nociceptive sensory neurons. Cell. 2001 Sep 7;106(5):619-32
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(22)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory