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Xpo6 Gene Detail
Summary
  • Symbol
    Xpo6
  • Name
    exportin 6
  • Synonyms
    2610005L19Rik, C230091E20Rik, mKIAA0370, Ranbp20
  • Feature Type
    protein coding gene
  • IDs
    MGI:2429950
    NCBI Gene: 74204
  • Gene Overview
    MyGene.info: XPO6
  • Alliance
    gene page
  • Transcription Start Sites
    12 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:126101715-126200501 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 69.01 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    589 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2429950
 protein coding gene Chr7:126101715-126200539 (-)
129S1/SvImJ MGP_129S1SvImJ_G0032973
 protein coding gene Chr7:130331644-130438896 (-)
A/J MGP_AJ_G0032956
 protein coding gene Chr7:126912408-127014948 (-)
AKR/J MGP_AKRJ_G0032888
 protein coding gene Chr7:130112524-130216322 (-)
BALB/cJ MGP_BALBcJ_G0032961
 protein coding gene Chr7:126568454-126669828 (-)
C3H/HeJ MGP_C3HHeJ_G0032671
 protein coding gene Chr7:130039572-130143734 (-)
C57BL/6NJ MGP_C57BL6NJ_G0033467
 protein coding gene Chr7:135413437-135525703 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0030439
 protein coding gene Chr7:128112915-128211851 (-)
CAST/EiJ MGP_CASTEiJ_G0031999
 protein coding gene Chr7:121831555-121937272 (-)
CBA/J MGP_CBAJ_G0032644
 protein coding gene Chr7:139962422-140079093 (-)
DBA/2J MGP_DBA2J_G0032796
 protein coding gene Chr7:124888474-124989361 (-)
FVB/NJ MGP_FVBNJ_G0032749
 protein coding gene Chr7:124733833-124834923 (-)
LP/J MGP_LPJ_G0032890
 protein coding gene Chr7:131793784-131905434 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0032781
 protein coding gene Chr7:141178247-141287057 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0033487
 protein coding gene Chr7:129118671-129222643 (-)
PWK/PhJ MGP_PWKPhJ_G0031707
 protein coding gene Chr7:117872798-117974473 (-)
SPRET/EiJ MGP_SPRETEiJ_G0031553
 protein coding gene Chr7:115940880-116048100 (-)
WSB/EiJ MGP_WSBEiJ_G0032112
 protein coding gene Chr7:130088467-130194412 (-)



Homology
more
  • Human Ortholog
    XPO6, exportin 6
  • Vertebrate Orthologs
    10
  • Human Ortholog
    XPO6, exportin 6
    Orthology source: HomoloGene, HGNC
  • Synonyms
    EXP6, RANBP20
  • Links
    NCBI Gene ID: 23214
    neXtProt AC: NX_Q96QU8
    UniProt: Q96QU8

  • Chr Location
    16p12.1; chr16:28097976-28211918 (-)  GRCh38.p7
  • HomoloGene
    Vertebrate Homology Class 12544
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: XPO6
  • Gene Tree
    Xpo6
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    15
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    631
  • cDNA Data
    183
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000000131 Ensembl Gene Model | MGI Sequence Detail 98787 C57BL/6J ±  kb
transcript ENSMUST00000168189 Ensembl | MGI Sequence Detail 4552 Not Applicable  
polypeptide ENSMUSP00000130527 Ensembl | MGI Sequence Detail 1125 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 184
    cDNA 184

    Microarray probesets 3
Other
Accession IDs
less
MGI:1921454, MGI:2142072, MGI:2142085, MGI:2142389
References
more
  • Summaries
    All 40
    Gene Ontology 7
    Phenotypes 8
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:241516 Fu B, et al., ZMPSTE24 defends against influenza and other pathogenic viruses. J Exp Med. 2017 Apr 03;214(4):919-929
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
10/13/2020
MGI 6.16 		The Jackson Laboratory