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Adamts16 Gene Detail
Summary
  • Symbol
    Adamts16
  • Name
    a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 16
  • Synonyms
    MGC:37086
  • Feature Type
    protein coding gene
  • IDs
    MGI:2429637
    NCBI Gene: 271127
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:70727802-70841811 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 13, 35.97 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1666 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2429637
protein coding gene Chr13:70727798-70841851 (-)
129S1/SvImJ MGP_129S1SvImJ_G0020737
protein coding gene Chr13:71046132-71166072 (-)
A/J MGP_AJ_G0020693
protein coding gene Chr13:68529811-68645425 (-)
AKR/J MGP_AKRJ_G0020668
protein coding gene Chr13:70738531-70855342 (-)
BALB/cJ MGP_BALBcJ_G0020690
protein coding gene Chr13:69057434-69178263 (-)
C3H/HeJ MGP_C3HHeJ_G0020485
protein coding gene Chr13:70425768-70544610 (-)
C57BL/6NJ MGP_C57BL6NJ_G0021127
protein coding gene Chr13:73488448-73606982 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0018695
protein coding gene Chr13:65431917-65550431 (-)
CAST/EiJ MGP_CASTEiJ_G0020002
protein coding gene Chr13:69428195-69562110 (-)
CBA/J MGP_CBAJ_G0020443
protein coding gene Chr13:76305188-76432964 (-)
DBA/2J MGP_DBA2J_G0020569
protein coding gene Chr13:68396276-68510771 (-)
FVB/NJ MGP_FVBNJ_G0020549
protein coding gene Chr13:67411213-67529914 (-)
LP/J MGP_LPJ_G0020641
protein coding gene Chr13:71317618-71435656 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0020577
protein coding gene Chr13:74725228-74844475 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0021166
protein coding gene Chr13:70022282-70142439 (-)
PWK/PhJ MGP_PWKPhJ_G0019756
protein coding gene Chr13:67101739-67219177 (-)
SPRET/EiJ MGP_SPRETEiJ_G0019579
protein coding gene Chr13:66517393-66645413 (-)
WSB/EiJ MGP_WSBEiJ_G0020059
protein coding gene Chr13:70531122-70648508 (-)



Homology
more
  • Human Ortholog
    ADAMTS16, ADAM metallopeptidase with thrombospondin type 1 motif 16
  • Vertebrate Orthologs
    9
  • Human Ortholog
    ADAMTS16, ADAM metallopeptidase with thrombospondin type 1 motif 16
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ADAMTS16s
  • Links
    NCBI Gene ID: 170690
    neXtProt AC: NX_Q8TE57
    UniProt: Q8TE57

  • Chr Location
    5p15.32; chr5:5140330-5320304 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000049538 Ensembl Gene Model | MGI Sequence Detail 114010 C57BL/6J ±  kb
transcript ENSMUST00000080145 Ensembl | MGI Sequence Detail 4981 Not Applicable  
polypeptide ENSMUSP00000079041 Ensembl | MGI Sequence Detail 1222 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 21
    cDNA 20
    Primer pair 1

    Microarray probesets 3
References
more
  • Summaries
    All 38
    Developmental Gene Expression 8
    Gene Ontology 4
    Phenotypes 8
  • Earliest
    J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
  • Latest
    J:261618 Cao M, et al., Metalloproteinase Adamts16 Is Required for Proper Closure of the Optic Fissure. Invest Ophthalmol Vis Sci. 2018 Mar 1;59(3):1167-1177

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory