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Pdzd3
Gene Detail
Symbol

Name
ID
Pdzd3
PDZ domain containing 3
MGI:2429554
Synonyms
NaPi-Cap2, Pdzk2, sodium-phosphate cotransporter IIa C-terminal-associated protein 2
Feature Type
protein coding gene
Genetic Map
Chromosome 9
24.84 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr9:44247312-44251464 bp, - strand
From NCBI annotation of GRCm38

  4153 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:11719  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 2 zebrafish

Gene Tree: Pdzd3

Human
homologs
Human Homolog PDZD3, PDZ domain containing 3
NCBI Gene ID 79849
neXtProt AC  NX_Q86UT5
Human Synonyms  IKEPP, NHERF4, PDZK2
Human Chr (Location)  11q23.3; chr11:119185418-119190223 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Gene trapped(1) Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Pdzd3 interacts with 157 markers (Mir1b, Mir17, Mir20a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (12 annotations)
Process negative regulation of guanylate cyclase activity
Component apical part of cell, brush border, ...
Function guanylate cyclase inhibitor activity, protein binding, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
cDNA source data(21)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(22) cDNA(21) Other(1)
Microarray probesets(2)
Other database
links
Ensembl Gene ModelENSMUSG00000032105 (Evidence)
Entrez Gene170761 (Evidence)
UniGene29872
DFCITC1583795
DoTSDT.40145987
NIA Mouse Gene IndexU030763
Consensus CDS ProjectCCDS23099.1
International Mouse Knockout Project StatusPdzd3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 170761 NCBI Gene Model | MGI Sequence Detail 4153 C57BL/6J ±  kb
transcript NM_133226 RefSeq | MGI Sequence Detail 2181 C57BL/6 
polypeptide Q99MJ6 UniProt | EBI | MGI Sequence Detail 498 Not Applicable 

For the selected sequences
All sequences(17) RefSeq(2) UniProt(1)
Polymorphisms
SNPs within 2kb(63 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001478 PDZ domain
Protein Ontology PR:000012527 Na(+)/H(+) exchange regulatory cofactor NHE-RF4
Graphical View of Protein Domain Structure
References
(Earliest) J:74952 Gisler SM, et al., Interaction of the type IIa Na/Pi cotransporter with PDZ proteins. J Biol Chem. 2001 Mar 23;276(12):9206-13
(Latest) J:190524 Shalom-Barak T, et al., Placental PPARgamma regulates spatiotemporally diverse genes and a unique metabolic network. Dev Biol. 2012 Dec 1;372(1):143-55
All references(31)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory