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Pdzd3
Gene Detail
Symbol

Name
ID
Pdzd3
PDZ domain containing 3
MGI:2429554
Synonyms
NaPi-Cap2, Pdzk2, sodium-phosphate cotransporter IIa C-terminal-associated protein 2
Feature Type
protein coding gene
Genetic Map
Chromosome 9
24.84 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr9:44247312-44251464 bp, - strand
From NCBI annotation of GRCm38

  4153 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:11719  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 2 zebrafish

HCOP human homology predictions: PDZD3
Gene Tree: Pdzd3

Human
homologs
PDZD3, PDZ domain containing 3
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 79849
neXtProt AC: NX_Q86UT5

Human Synonyms: IKEPP, NHERF4, PDZK2

Human Chr (Location): 11q23.3; chr11:119185436-119190223 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Gene trapped(1) Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Pdzd3 interacts with 156 markers (Mir1b, Mir17, Mir20a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (12 annotations)
Process negative regulation of guanylate cyclase activity
Component apical part of cell, brush border, ...
Function guanylate cyclase inhibitor activity, protein binding, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
cDNA source data(21)
Other mouse links: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(22) cDNA(21) Other(1)
Microarray probesets(2)
Other database
links
Ensembl Gene Model ENSMUSG00000032105 (Evidence)
Entrez Gene 170761 (Evidence)
UniGene 29872
DFCI TC1583795
DoTS DT.40145987
NIA Mouse Gene Index U030763
Consensus CDS Project CCDS23099.1
International Mouse Phenotyping Consortium Status Pdzd3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 170761 NCBI Gene Model | MGI Sequence Detail 4153 C57BL/6J ±  kb
transcript NM_133226 RefSeq | MGI Sequence Detail 2181 C57BL/6 
polypeptide Q99MJ6 UniProt | EBI | MGI Sequence Detail 498 Not Applicable 

For the selected sequences
All sequences(17) RefSeq(2) UniProt(1)
Polymorphisms
SNPs within 2kb(63 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001478 PDZ domain
Protein Ontology PR:000012527 Na(+)/H(+) exchange regulatory cofactor NHE-RF4
Graphical View of Protein Domain Structure
References
(Earliest) J:74952 Gisler SM, et al., Interaction of the type IIa Na/Pi cotransporter with PDZ proteins. J Biol Chem. 2001 Mar 23;276(12):9206-13
(Latest) J:190524 Shalom-Barak T, et al., Placental PPARgamma regulates spatiotemporally diverse genes and a unique metabolic network. Dev Biol. 2012 Dec 1;372(1):143-55
All references(30)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory