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Adam1a Gene Detail
Summary
  • Symbol
    Adam1a
  • Name
    a disintegrin and metallopeptidase domain 1a
  • Synonyms
    fertilin alpha, Ftna, PH-30 alpha
  • Feature Type
    protein coding gene
  • IDs
    MGI:2429504
    NCBI Gene: 280668
  • Alliance
Location & Maps
more
  • Sequence Map
    Chr5:121518576-121522071 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      3496 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 61.84 cM
  • Mapping Data
    5 experiments
Homology
more
  • Human Ortholog
    ADAM1A, ADAM metallopeptidase domain 1A (pseudogene)
  • Vertebrate Orthologs
    5
  • Human Ortholog
    ADAM1A, ADAM metallopeptidase domain 1A (pseudogene)
    Orthology source: HGNC
  • Synonyms
    ADAM1, ADAM1P, Ftna, FTNAP, PH-30a
  • Links
    NCBI Gene ID: 8759

  • Chr Location
    12q24.12-q24.13; chr12:111899063-111901902 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    4
  • Chemically induced (other)
    1
  • Radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    2 involving Adam1a
  • Incidental Mutations
    APF , CvDC
  • Find Mice (IMSR)
Homozygous null mice display male infertility with asthenozoospermia.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000023479 VEGA Gene Model | MGI Sequence Detail 3496 C57BL/6J ±  kb
transcript OTTMUST00000057126 VEGA | MGI Sequence Detail 3496 Not Applicable  
polypeptide OTTMUSP00000027523 VEGA | MGI Sequence Detail 791 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    22 from dbSNP Build 142
  • RFLP
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 21
    Genomic 3
    cDNA 18

    Microarray probesets 4
References
more
  • Summaries
    All 35
    Gene Ontology 1
    Phenotypes 8
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/10/2018
MGI 6.12
The Jackson Laboratory