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Fmo4 Gene Detail
Summary
  • Symbol
    Fmo4
  • Name
    flavin containing monooxygenase 4
  • Feature Type
    protein coding gene
  • IDs
    MGI:2429497
    NCBI Gene: 226564
  • Gene Overview
    MyGene.info: FMO4
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:162793188-162813972 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 70.34 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    231 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2429497
protein coding gene Chr1:162793188-162815869 (-)
129S1/SvImJ MGP_129S1SvImJ_G0016664
protein coding gene Chr1:168155593-168175450 (-)
A/J MGP_AJ_G0016645
protein coding gene Chr1:161308350-161328525 (-)
AKR/J MGP_AKRJ_G0016611
protein coding gene Chr1:166189727-166208378 (-)
BALB/cJ MGP_BALBcJ_G0016606
protein coding gene Chr1:161826931-161845476 (-)
C3H/HeJ MGP_C3HHeJ_G0016430
protein coding gene Chr1:166393236-166414838 (-)
C57BL/6NJ MGP_C57BL6NJ_G0017067
protein coding gene Chr1:173804004-173822618 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014776
protein coding gene Chr1:153346223-153365463 (-)
CAST/EiJ MGP_CASTEiJ_G0016010
protein coding gene Chr1:166046704-166066252 (-)
CBA/J MGP_CBAJ_G0016405
protein coding gene Chr1:179998934-180019871 (-)
DBA/2J MGP_DBA2J_G0016511
protein coding gene Chr1:160241658-160261073 (-)
FVB/NJ MGP_FVBNJ_G0016509
protein coding gene Chr1:158670312-158688814 (-)
LP/J MGP_LPJ_G0016582
protein coding gene Chr1:169260484-169284271 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0016534
protein coding gene Chr1:187503939-187526890 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0017103
protein coding gene Chr1:166019823-166040313 (-)
PWK/PhJ MGP_PWKPhJ_G0015796
protein coding gene Chr1:159424248-159444000 (-)
SPRET/EiJ MGP_SPRETEiJ_G0015583
protein coding gene Chr1:164877418-164884566 (+)
WSB/EiJ MGP_WSBEiJ_G0016072
protein coding gene Chr1:166200080-166225175 (-)



Homology
more
  • Human Ortholog
    FMO4, flavin containing monooxygenase 4
  • Vertebrate Orthologs
    9
  • Human Ortholog
    FMO4, flavin containing monooxygenase 4
    Orthology source: HomoloGene, HGNC
  • Synonyms
    FMO2
  • Links
    NCBI Gene ID: 2329
    neXtProt AC: NX_P31512
    UniProt: P31512

  • Chr Location
    1q24.3; chr1:171314131-171342084 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000026692 Ensembl Gene Model | MGI Sequence Detail 20785 C57BL/6J ±  kb
transcript ENSMUST00000111525 Ensembl | MGI Sequence Detail 2683 Not Applicable  
polypeptide ENSMUSP00000107150 Ensembl | MGI Sequence Detail 560 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 6
    Genomic 2
    cDNA 4

    Microarray probesets 3
References
more
  • Summaries
    All 31
    Developmental Gene Expression 1
    Gene Ontology 6
    Phenotypes 9
  • Earliest
    J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
  • Latest
    J:214341 Veeravalli S, et al., The phenotype of a flavin-containing monooyxgenase knockout mouse implicates the drug-metabolizing enzyme FMO1 as a novel regulator of energy balance. Biochem Pharmacol. 2014 Jul 1;90(1):88-95

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/13/2018
MGI 6.13
The Jackson Laboratory