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Afm
Gene Detail
Symbol

Name
ID
Afm
afamin
MGI:2429409
Synonyms
Alf, alpha albumin
Feature Type
protein coding gene
Genetic Map
Chromosome 5
44.78 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr5:90518932-90553543 bp, + strand
From VEGA annotation of GRCm38

  34612 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:881  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog

Protein SuperFamily: serum albumin
Gene Tree: Afm

Human
homologs
Human Homolog AFM, afamin
NCBI Gene ID 173
neXtProt AC  NX_P43652
Human Synonyms  ALB2, ALBA, ALF
Human Chr (Location)  4q13.3; chr4:73481740-73504001 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Afm interacts with 184 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (9 annotations)
Process transport, vitamin transport
Component blood microparticle, extracellular region, ...
Function vitamin E binding
External Resources: FuncBase
Expression
Literature Summary: (4 records)
Data Summary: Results (102)    Tissues (60)    Images (21)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 98
RT-PCR 4
cDNA source data(59)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(60) cDNA(59) Primer pair(1)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000033292 (Evidence)
Ensembl Gene ModelENSMUSG00000029369 (Evidence)
Entrez Gene280662 (Evidence)
UniGene348786
DFCITC1579673, TC1674123
DoTSDT.534669, DT.94370808
NIA Mouse Gene IndexU005778
Consensus CDS ProjectCCDS39141.1
International Mouse Knockout Project StatusAfm
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000033292 VEGA Gene Model | MGI Sequence Detail 34612 C57BL/6J ±  kb
transcript OTTMUST00000083498 VEGA | MGI Sequence Detail 2038 Not Applicable 
polypeptide OTTMUSP00000044892 VEGA | MGI Sequence Detail 608 Not Applicable 

For the selected sequences
All sequences(25) RefSeq(2) UniProt(1)
Polymorphisms
SNPs within 2kb(127 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000264 ALB/AFP/VDB
InterPro IPR001703 Alpha-fetoprotein
InterPro IPR021177 Serum albumin/Alpha-fetoprotein
InterPro IPR020857 Serum albumin, conserved site
InterPro IPR020858 Serum albumin-like
InterPro IPR014760 Serum albumin, N-terminal
Protein Ontology PR:000003808 afamin
References
(Earliest) J:79500 Gabant P, et al., Alpha-fetoprotein, the major fetal serum protein, is not essential for embryonic development but is required for female fertility. Proc Natl Acad Sci U S A. 2002 Oct 1;99(20):12865-70
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(32)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/21/2014
MGI 5.20
The Jackson Laboratory