Slc17a3 MGI Mouse Gene Detail - MGI:2389216 - solute carrier family 17 (sodium phosphate), member 3

Symbol

Slc17a3
Name

solute carrier family 17 (sodium phosphate), member 3
Synonyms

Npt4

Feature Type

protein coding gene
IDs

MGI:2389216
NCBI Gene: 105355
Alliance

gene page
Transcription Start Sites

6 TSS

Sequence Map

Chr13:24023417-24044699 bp, + strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 13, 9.95 cM
Mapping Data

2 experiments

SNPs within 2kb

278 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_2389216	protein coding gene	Chr13:24020905-24044701 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0020370	protein coding gene	Chr13:21286550-21310032 (+)
A/J	MGP_AJ_G0020319	protein coding gene	Chr13:20893231-20915393 (+)
AKR/J	MGP_AKRJ_G0020299	protein coding gene	Chr13:21147219-21168530 (+)
BALB/cJ	MGP_BALBcJ_G0020317	protein coding gene	Chr13:20893139-20908796 (+)
C3H/HeJ	MGP_C3HHeJ_G0020121	protein coding gene	Chr13:21223390-21239075 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0020754	protein coding gene	Chr13:22067759-22089036 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0018342	protein coding gene	Chr13:19668861-19692903 (+)
CAST/EiJ	MGP_CASTEiJ_G0019638	protein coding gene	Chr13:20904525-20926971 (+)
CBA/J	MGP_CBAJ_G0020075	protein coding gene	Chr13:22927002-22942677 (+)
DBA/2J	MGP_DBA2J_G0020201	protein coding gene	Chr13:20424320-20440004 (+)
FVB/NJ	MGP_FVBNJ_G0020185	protein coding gene	Chr13:20072511-20093808 (+)
LP/J	MGP_LPJ_G0020274	protein coding gene	Chr13:21598738-21614334 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0020212	protein coding gene	Chr13:23216229-23237460 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0020796	protein coding gene	Chr13:21002335-21020941 (+)
PWK/PhJ	MGP_PWKPhJ_G0019392	protein coding gene	Chr13:20454368-20475858 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0019209	protein coding gene	Chr13:19810439-19832294 (+)
WSB/EiJ	MGP_WSBEiJ_G0019698	protein coding gene	Chr13:21141043-21163054 (+)

Human Ortholog

SLC17A3, solute carrier family 17 member 3

Vertebrate Orthologs

2

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

SLC17A3, solute carrier family 17 member 3
Synonyms

GOUT4, NPT4, UAQTL4
Links

HGNC:10931

NCBI Gene ID: 10786

neXtProt AC: NX_O00476

UniProt: O00476
Chr Location

6p22.2; chr6:25845100-25874243 (-) GRCh38.p7

Alliance of Genome Resources

Slc17a3 stringent orthology
1 human;1 mouse;1 rat
HCOP

vertebrate homology predictions: SLC17A3
Protein SuperFamily

Na(+)/PI_cotransporter4_prd
Gene Tree

Slc17a3

less

Phenotype Summary

13 phenotype references

All Mutations and Alleles

7
Chemically induced (other)

1
Radiation induced

1
Targeted

5
Genomic Mutations

2 involving Slc17a3
Incidental Mutations

Mutagenetix , APF
Find Mice (IMSR)

37 strains or lines available

less

All GO Annotations

29
GO References

2

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell death	cell differentiation	cell population proliferation	cellular component organization	establishment of localization	homeostatic process	immune system process	lipid metabolic process	nucleic acid-templated transcription	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	non-membrane-bounded organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

less

Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

748
Tissues

62
cDNA Data

56
Literature Summary

3

Images

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas

less

Slc17a3 interacts with 295 markers (Mir7-1, Mir7-2, Mir7b, ...) View All

less

All Sequences

58
RefSeq

13
UniProt

4
CCDS

CCDS26371.1, CCDS49220.1

Ensembl

ENSMUSG00000036083 (Evidence)
NCBI Gene

105355

Representative Sequences				Length	Strain/Species	Flank
	genomic	ENSMUSG00000036083	Ensembl Gene Model \| MGI Sequence Detail	21283	C57BL/6J	± kb

less

UniProt

4 Sequences
InterPro Domains

IPR011701 Major facilitator superfamily

IPR020846 Major facilitator superfamily domain

IPR036259 MFS transporter superfamily

IPR017373 Sodium-dependent phosphate transport protein 4 , predicted

less

All nucleic 56

cDNA 56

Microarray probesets 3

less

MGI:2145426

Summaries

All 35

Developmental Gene Expression 3

Gene Ontology 2

Phenotypes 13
Earliest

J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
Latest

J:236599 Dickinson ME, et al., High-throughput discovery of novel developmental phenotypes. Nature. 2016 Sep 14;537(7621):508-514

TSS for Slc17a3:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr118875	Chr13:24023384-24023425 (+)	-12 bp
Tssr118876	Chr13:24023428-24023453 (+)	24 bp
Tssr118877	Chr13:24023560-24023570 (+)	148 bp
Tssr118878	Chr13:24023581-24023603 (+)	175 bp
Tssr4011	Chr13:24023608-24023611 (+)	193 bp
Tssr4012	Chr13:24023706-24023715 (+)	294 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer & Copyright Notice Send questions and comments to User Support.	last database update 05/10/2022 MGI 6.19