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Adamtsl4
Gene Detail
 Symbol
Name
ID
Adamtsl4
ADAMTS-like 4
MGI:2389008
Synonyms Tsrc1
Feature Type protein coding gene
Genetic Map
Chromosome 3
40.74 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr3:95676201-95687917 bp, - strand
From VEGA annotation of GRCm38

  11717 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:23141  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 zebrafish

Gene Tree: Adamtsl4

Human
homologs
Human Homolog ADAMTSL4, ADAMTS-like 4
NCBI Gene ID 54507
neXtProt AC  NX_Q6UY14
Human Synonyms  ADAMTSL-4, ECTOL2, TSRC1
Human Chr (Location)  1q21.3; chr1:150549369-150560937 (+)  GRCh38
Disease Associations  (2) Diseases Associated with Human ADAMTSL4
Mutations,
alleles, and
phenotypes
All mutations/alleles(28) : Gene trapped(26) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Adamtsl4 interacts with 131 markers (Mir7b, Mir10b, Mir22, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (10 annotations)
Process apoptotic process, extracellular matrix organization, ...
Component extracellular matrix, extracellular region, ...
Function metalloendopeptidase activity, peptidase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (23)    Tissues (16)   
Theiler Stages: 11, 21, 22, 28
Assay TypeResults
Northern blot 9
RT-PCR 14
cDNA source data(17)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(19) cDNA(17) Primer pair(2)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000027489 (Evidence)
Ensembl Gene ModelENSMUSG00000015850 (Evidence)
Entrez Gene229595 (Evidence)
UniGene490574
DFCITC1577440
DoTSDT.99838780, DT.99856673
NIA Mouse Gene IndexU024367
Consensus CDS ProjectCCDS17618.1
International Mouse Knockout Project StatusAdamtsl4
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000027489 VEGA Gene Model | MGI Sequence Detail 11717 C57BL/6J ±  kb
transcript OTTMUST00000068031 VEGA | MGI Sequence Detail 4036 Not Applicable 
polypeptide OTTMUSP00000034317 VEGA | MGI Sequence Detail 1036 Not Applicable 

For the selected sequences
All sequences(48) RefSeq(14) UniProt(3)
Polymorphisms SNPs within 2kb(68 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR010294 ADAM-TS Spacer 1
InterPro IPR010909 PLAC
InterPro IPR000884 Thrombospondin, type 1 repeat
Protein Ontology PR:000003741 ADAMTS-like protein 4
References (Earliest) J:83212 Buchner DA, et al., TSRC1, a widely expressed gene containing seven thrombospondin type I repeats. Gene. 2003 Mar 27;307:23-30
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(32)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory