Adamtsl4
Gene Detail

Symbol Name ID

Adamtsl4 ADAMTS-like 4 MGI:2389008

Synonyms

Tsrc1

Feature Type

protein coding gene

Genetic Map

Chromosome 3

40.74 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)

Sequence Map

Chr3:95676201-95687917 bp, - strand From VEGA annotation of GRCm38   11717 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:23141  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog

Gene Tree: Adamtsl4

Human homologs

Human Homolog		ADAMTSL4, ADAMTS-like 4
NCBI Gene ID		54507
neXtProt AC		NX_Q6UY14
Human Synonyms		ECTOL2, TSRC1
Human Chr (Location)		1q21.3; chr1:150521898-150533413 (+)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human ADAMTSL4

Alleles and phenotypes

All alleles(28) : Targeted(2) Gene trapped(26)

Gene Ontology (GO) classifications

All GO classifications: (10 annotations)

Process	apoptotic process, extracellular matrix organization, ...
Component	extracellular matrix, extracellular region, ...
Function	metalloendopeptidase activity, peptidase activity, ...

External Resources: FuncBase

Expression

Literature Summary: (2 records)
Data Summary: Results (23)    Tissues (16)   
Theiler Stages: 11, 21, 22, 28

Assay Type	Results
Northern blot	9
RT-PCR	14

cDNA source data(17)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(19) cDNA(17) Primer pair(2)
Microarray probesets(3)

Other database links

VEGA Gene Model	OTTMUSG00000027489 (Evidence)
Ensembl Gene Model	ENSMUSG00000015850 (Evidence)
Entrez Gene	229595 (Evidence)
UniGene	485967
DFCI	TC1577440
DoTS	DT.99838780, DT.99856673
NIA Mouse Gene Index	U024367
Consensus CDS Project	CCDS17618.1
International Mouse Knockout Project Status	Adamtsl4

Sequences

Length	Strain/Species
genomic	OTTMUSG00000027489	VEGA Gene Model | MGI Sequence Detail	11717	C57BL/6J
transcript	OTTMUST00000068031	VEGA | MGI Sequence Detail	4036	Not Applicable
polypeptide	OTTMUSP00000034317	VEGA | MGI Sequence Detail	1036	Not Applicable

All sequences(36) RefSeq(2) UniProt(3)

Polymorphisms

SNPs(49 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR010294	ADAM-TS Spacer 1
InterPro	IPR010909	PLAC
InterPro	IPR000884	Thrombospondin, type 1 repeat
Protein Ontology	PR:000003741	ADAMTS-like protein 4

References

(Earliest) J:83212 Buchner DA, et al., TSRC1, a widely expressed gene containing seven thrombospondin type I repeats. Gene. 2003 Mar 27;307:23-30
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(32)