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Sgcz Gene Detail
Summary
  • Symbol
    Sgcz
  • Name
    sarcoglycan zeta
  • Synonyms
    C230085N17Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2388820
    NCBI Gene: 244431
  • Gene Overview
    MyGene.info: SGCZ
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:37522298-38661508 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 8, 23.31 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    13262 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2388820
protein coding gene Chr8:37517840-38662638 (-)
129S1/SvImJ MGP_129S1SvImJ_G0033547
protein coding gene Chr8:36235559-37462034 (-)
A/J MGP_AJ_G0033527
protein coding gene Chr8:34867732-36031153 (-)
AKR/J MGP_AKRJ_G0033451
protein coding gene Chr8:35946270-37112866 (-)
BALB/cJ MGP_BALBcJ_G0033523
protein coding gene Chr8:34967862-36124582 (-)
C3H/HeJ MGP_C3HHeJ_G0033235
protein coding gene Chr8:36320919-37506301 (-)
C57BL/6NJ MGP_C57BL6NJ_G0034039
protein coding gene Chr8:37590655-38854476 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0030988
protein coding gene Chr8:31732938-32769307 (-)
CAST/EiJ MGP_CASTEiJ_G0032563
protein coding gene Chr8:35743965-36982628 (-)
CBA/J MGP_CBAJ_G0033213
protein coding gene Chr8:39112400-40433985 (-)
DBA/2J MGP_DBA2J_G0033366
protein coding gene Chr8:34776795-35910818 (-)
FVB/NJ MGP_FVBNJ_G0033311
protein coding gene Chr8:34400328-35499401 (-)
LP/J MGP_LPJ_G0033456
protein coding gene Chr8:36250524-37485300 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0033353
protein coding gene Chr8:38471171-40143975 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0034058
protein coding gene Chr8:36050912-37256825 (-)
PWK/PhJ MGP_PWKPhJ_G0032272
protein coding gene Chr8:34309783-35443474 (-)
SPRET/EiJ MGP_SPRETEiJ_G0032104
protein coding gene Chr8:35319677-36473311 (-)
WSB/EiJ MGP_WSBEiJ_G0032678
protein coding gene Chr8:36268159-37454062 (-)



Homology
more
  • Human Ortholog
    SGCZ, sarcoglycan zeta
  • Vertebrate Orthologs
    9
  • Human Ortholog
    SGCZ, sarcoglycan zeta
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ZSG1
  • Links
    NCBI Gene ID: 137868
    neXtProt AC: NX_Q96LD1
    UniProt: Q96LD1

  • Chr Location
    8p22; chr8:14084835-15238283 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000039539 Ensembl Gene Model | MGI Sequence Detail 1139211 C57BL/6J ±  kb
transcript ENSMUST00000118896 Ensembl | MGI Sequence Detail 2389 Not Applicable  
polypeptide ENSMUSP00000113912 Ensembl | MGI Sequence Detail 311 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 9
    cDNA 9

    Microarray probesets 1
Other
Accession IDs
less
MGI:2444342
References
more
  • Summaries
    All 28
    Gene Ontology 5
    Phenotypes 4
  • Earliest
    J:79436 Wheeler MT, et al., zeta-Sarcoglycan, a novel component of the sarcoglycan complex, is reduced in muscular dystrophy. Hum Mol Genet. 2002 Sep 1;11(18):2147-54
  • Latest
    J:240008 Levy R, et al., Collaborative cross mice in a genetic association study reveal new candidate genes for bone microarchitecture. BMC Genomics. 2015 Nov 26;16:1013

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory