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Plekha6 Gene Detail
Summary
  • Symbol
    Plekha6
  • Name
    pleckstrin homology domain containing, family A member 6
  • Synonyms
    Pepp3
  • Feature Type
    protein coding gene
  • IDs
    MGI:2388662
    NCBI Gene: 240753
  • Gene Overview
    MyGene.info: PLEKHA6
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:133164210-133303435 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 57.91 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    820 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2388662
protein coding gene Chr1:133163768-133303435 (.)
129S1/SvImJ MGP_129S1SvImJ_G0016481
protein coding gene Chr1:136778456-136838254 (+)
A/J MGP_AJ_G0016464
protein coding gene Chr1:131702367-131761245 (+)
AKR/J MGP_AKRJ_G0016429
protein coding gene Chr1:135586198-135647381 (+)
BALB/cJ MGP_BALBcJ_G0016424
protein coding gene Chr1:131967700-132091872 (+)
C3H/HeJ MGP_C3HHeJ_G0016250
protein coding gene Chr1:135720427-135780254 (+)
C57BL/6NJ MGP_C57BL6NJ_G0016885
protein coding gene Chr1:141844387-141905893 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0014596
protein coding gene Chr1:124856477-124913507 (+)
CAST/EiJ MGP_CASTEiJ_G0015830
protein coding gene Chr1:134748325-134807810 (+)
CBA/J MGP_CBAJ_G0016222
protein coding gene Chr1:146671057-146728181 (+)
DBA/2J MGP_DBA2J_G0016329
protein coding gene Chr1:130672945-130730292 (+)
FVB/NJ MGP_FVBNJ_G0016328
protein coding gene Chr1:129314092-129371328 (+)
LP/J MGP_LPJ_G0016400
protein coding gene Chr1:138089928-138147751 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0016353
protein coding gene Chr1:152452188-152511693 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0016921
protein coding gene Chr1:135327049-135385358 (+)
PWK/PhJ MGP_PWKPhJ_G0015616
protein coding gene Chr1:129677681-129736360 (+)
SPRET/EiJ MGP_SPRETEiJ_G0015403
protein coding gene Chr1:134203021-134345556 (+)
WSB/EiJ MGP_WSBEiJ_G0015892
protein coding gene Chr1:135336456-135395846 (+)



Homology
more
  • Human Ortholog
    PLEKHA6, pleckstrin homology domain containing A6
  • Vertebrate Orthologs
    5
  • Human Ortholog
    PLEKHA6, pleckstrin homology domain containing A6
    Orthology source: HGNC
  • Synonyms
    PEPP3, PEPP-3
  • Links
    NCBI Gene ID: 22874
    neXtProt AC: NX_Q9Y2H5
    UniProt: Q9Y2H5

  • Chr Location
    1q32.1; chr1:204218851-204378376 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
Gene Ontology
(GO)
Classifications
less
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000041757 Ensembl Gene Model | MGI Sequence Detail 139226 C57BL/6J ±  kb
transcript ENSMUST00000038295 Ensembl | MGI Sequence Detail 7388 Not Applicable  
polypeptide ENSMUSP00000048214 Ensembl | MGI Sequence Detail 1173 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 78
    cDNA 77
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:2138495
References
more
  • Summaries
    All 33
    Developmental Gene Expression 2
    Phenotypes 10
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:256807 Ushiki A, et al., Long-Range Control of Renin Gene Expression in Tsukuba Hypertensive Mice. PLoS One. 2016;11(11):e0166974

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory