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Ppp2r5d
Gene Detail
 Symbol
Name
ID
Ppp2r5d
protein phosphatase 2, regulatory subunit B', delta
MGI:2388481
Synonyms B'delta, TEG-271, Tex271
Feature Type protein coding gene
Genetic Map
Chromosome 17
22.90 cM, cytoband C
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr17:46682991-46705002 bp, - strand
From NCBI annotation of GRCm38

  22012 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:37661  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: serine/threonine-protein phosphatase 2A, subunit B56
Gene Tree: Ppp2r5d

Human
homologs
Human Homolog PPP2R5D, protein phosphatase 2, regulatory subunit B', delta
NCBI Gene ID 5528
neXtProt AC  NX_Q14738
Human Synonyms  B56D
Human Chr (Location)  6p21.1; chr6:42984499-43012345 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(17) : Gene trapped(14) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a gene-trap allele exhibit lethality, while heterozygous mice display decreased prepulse inhibition. Mice homozygous for a targeted knock-out allele exhibit decreased thermal nociception threshold, impaired coordination, and increased latency to removing an adhesive sticker.
 
Interactions
Ppp2r5d interacts with 180 markers (Mir9-1, Mir9-2, Mir9-3, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (8 annotations)
Process cellular response to growth factor stimulus, positive regulation of neuron projection development, ...
Function protein binding
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (21)    Tissues (21)   
Theiler Stages: 10, 18, 22, 23, 25, 28
Assay TypeResults
RNA in situ 7
Northern blot 14
cDNA source data(5)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(6) cDNA(5) Primer pair(1)
Microarray probesets(3)
Other database
links
Ensembl Gene ModelENSMUSG00000059409 (Evidence)
Entrez Gene21770 (Evidence)
DFCITC1572632, TC1596496, TC1603599
Consensus CDS ProjectCCDS28836.1
International Mouse Knockout Project StatusPpp2r5d
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 21770 NCBI Gene Model | MGI Sequence Detail 22012 C57BL/6J ±  kb
transcript NM_009358 RefSeq | MGI Sequence Detail 2926 C57BL/6 
polypeptide NP_033384 RefSeq | MGI Sequence Detail 594 C57BL/6 

For the selected sequences
All sequences(40) RefSeq(4) UniProt(6)
Polymorphisms SNPs within 2kb(80 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR016024 Armadillo-type fold
InterPro IPR002554 Protein phosphatase 2A, regulatory B subunit, B56
Protein Ontology PR:000013146 serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform
References (Earliest) J:35463 Lopez-Fernandez LA, et al., Characterization of genes expressed early in mouse spermatogenesis, isolated from a subtractive cDNA library. Mamm Genome. 1996 Sep;7(9):698-700
(Latest) J:188568 Tadmouri A, et al., Cacnb4 directly couples electrical activity to gene expression, a process defective in juvenile epilepsy. EMBO J. 2012 Sep 12;31(18):3730-44
All references(35)
Other
accession IDs
MGI:1096565

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory