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Ppp2r5b Gene Detail
Summary
  • Symbol
    Ppp2r5b
  • Name
    protein phosphatase 2, regulatory subunit B', beta
  • Synonyms
    B'beta
  • Feature Type
    protein coding gene
  • IDs
    MGI:2388480
    NCBI Gene: 225849
  • Gene Overview
    MyGene.info: PPP2R5B
Location & Maps
more
  • Genetic Map
    Chromosome 19, 4.35 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    PPP2R5B, protein phosphatase 2 regulatory subunit B'beta
  • Vertebrate Orthologs
    9
  • Human Ortholog
    PPP2R5B, protein phosphatase 2 regulatory subunit B'beta
    Orthology source: HGNC, HomoloGene
  • Synonyms
    B56B, PR61B
  • Links
    NCBI Gene ID: 5526
    neXtProt AC: NX_Q15173

  • Chr Location
    11q12; chr11:64917553-64934478 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000018606 VEGA Gene Model | MGI Sequence Detail 8108 C57BL/6J ±  kb
transcript OTTMUST00000044776 VEGA | MGI Sequence Detail 2742 Not Applicable  
polypeptide OTTMUSP00000020148 VEGA | MGI Sequence Detail 497 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    50 from dbSNP Build 142
Protein
Information
less
  • UniProt
    3 Sequences
  • InterPro Domains
    IPR016024 Armadillo-type fold
    IPR002554 Protein phosphatase 2A, regulatory B subunit, B56
Molecular
Reagents
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  • All nucleic 10
    cDNA 9
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
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MGI:2446182
References
more
  • Summaries
    All 27
    Developmental Gene Expression 3
    Gene Ontology 1
    Phenotypes 5
  • Earliest
    J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory