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Pkn3
Gene Detail
Symbol

Name
ID
Pkn3
protein kinase N3
MGI:2388285
Feature Type
protein coding gene
Genetic Map
Chromosome 2
21.13 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr2:30077684-30091022 bp, + strand
From VEGA annotation of GRCm38

  13339 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:50980  Vertebrate Homology Class
1 human; 1 mouse; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog

Gene Tree: Pkn3

Human
homologs
Human Homolog PKN3, protein kinase N3
NCBI Gene ID 29941
neXtProt AC  NX_Q6P5Z2
Human Chr (Location)  9q34.11; chr9:128702235-128720920 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(8) : Gene trapped(6) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Pkn3 interacts with 66 markers (Mir15a, Mir15b, Mir16-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (16 annotations)
Process epithelial cell migration, phosphorylation, ...
Component cytoplasm, nucleus
Function ATP binding, kinase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (10)    Tissues (1)    Images (10)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 10
cDNA source data(6)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(6) cDNA(6)
Microarray probesets(2)
Other database
links
VEGA Gene ModelOTTMUSG00000016746 (Evidence)
Ensembl Gene ModelENSMUSG00000026785 (Evidence)
Entrez Gene263803 (Evidence)
EC2.7.11.13
Consensus CDS ProjectCCDS15867.1
International Mouse Knockout Project StatusPkn3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000016746 VEGA Gene Model | MGI Sequence Detail 13339 C57BL/6J ±  kb
transcript OTTMUST00000040621 VEGA | MGI Sequence Detail 3113 Not Applicable 
polypeptide OTTMUSP00000018153 VEGA | MGI Sequence Detail 878 Not Applicable 

For the selected sequences
All sequences(48) RefSeq(10) UniProt(7)
Polymorphisms
SNPs within 2kb(46 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000961 AGC-kinase, C-terminal
InterPro IPR000008 C2 calcium-dependent membrane targeting
InterPro IPR011072 HR1 rho-binding repeat
InterPro IPR017441 Protein kinase, ATP binding site
InterPro IPR000719 Protein kinase, catalytic domain
InterPro IPR017892 Protein kinase, C-terminal
InterPro IPR011009 Protein kinase-like domain
InterPro IPR002290 Serine/threonine- / dual specificity protein kinase, catalytic domain
InterPro IPR008271 Serine/threonine-protein kinase, active site
Protein Ontology PR:000012787 serine/threonine-protein kinase N3
References
(Earliest) J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(29)
Other
accession IDs
MGI:2139325

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory