Camk1g
Gene Detail

Symbol Name ID

Camk1g calcium/calmodulin-dependent protein kinase I gamma MGI:2388073

Synonyms

CaMKIgamma, CLICK-III

Feature Type

protein coding gene

Genetic Map

Chromosome 1

97.74 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr1:193346346-193370297 bp, - strand From VEGA annotation of GRCm38   23952 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:48706  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 2 zebrafish

Protein SuperFamily: kinase-related transforming protein
Gene Tree: Camk1g

Human homologs

Human Homolog		CAMK1G, calcium/calmodulin-dependent protein kinase IG
NCBI Gene ID		57172
neXtProt AC		NX_Q96NX5
Human Synonyms		CLICK3, CLICKIII, dJ272L16.1, VWS1
Human Chr (Location)		1q32.2; chr1:209757045-209787284 (+)  GRCh37.p10

Alleles and phenotypes

All alleles(5) : Targeted(5)
 

Mice homozygous for a knock-out allele exhibit impaired dendritogenesis.

 

Gene Ontology (GO) classifications

All GO classifications: (26 annotations)

Process	metabolic process, phosphorylation, ...
Component	calcium- and calmodulin-dependent protein kinase complex, cytoplasm, ...
Function	ATP binding, calmodulin binding, ...

External Resources: FuncBase

Expression

Literature Summary: (5 records)
Data Summary: Results (88)    Tissues (46)    Images (29)
Theiler Stages: 10, 18, 19, 23, 25, 28

Assay Type	Results
RNA in situ	66
Northern blot	22

cDNA source data(20)
External Resources: Allen Institute   GENSAT   GEO   ArrayExpress

Molecular reagents

All nucleic(22) cDNA(20) Primer pair(2)
Microarray probesets(2)

Other database links

VEGA Gene Model	OTTMUSG00000035816 (Evidence)
Ensembl Gene Model	ENSMUSG00000016179 (Evidence)
Entrez Gene	215303 (Evidence)
UniGene	40329
DFCI	TC1582790
DoTS	DT.60104839
NIA Mouse Gene Index	U022224
EC	2.7.11.17
Consensus CDS Project	CCDS15638.1
International Mouse Knockout Project Status	Camk1g

Sequences

Length	Strain/Species
genomic	OTTMUSG00000035816	VEGA Gene Model | MGI Sequence Detail	23952	C57BL/6J
transcript	OTTMUST00000091733	VEGA | MGI Sequence Detail	2468	Not Applicable
polypeptide	OTTMUSP00000050553	VEGA | MGI Sequence Detail	477	Not Applicable

All sequences(34) RefSeq(2) UniProt(4)

Polymorphisms

SNPs(243 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR020636	Calcium/calmodulin-dependent/calcium-dependent protein kinase
InterPro	IPR017441	Protein kinase, ATP binding site
InterPro	IPR000719	Protein kinase, catalytic domain
InterPro	IPR011009	Protein kinase-like domain
InterPro	IPR002290	Serine/threonine- / dual-specificity protein kinase, catalytic domain
InterPro	IPR008271	Serine/threonine-protein kinase, active site
Protein Ontology	PR:000004990	calcium/calmodulin-dependent protein kinase type 1G

References

(Earliest) J:83600 Takemoto-Kimura S, et al., Molecular cloning and characterization of CLICK-III/CaMKIgamma, a novel membrane-anchored neuronal Ca2+/calmodulin-dependent protein kinase (CaMK). J Biol Chem. 2003 May 16;278(20):18597-605
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(33)