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Stoml3
Gene Detail
Symbol

Name
ID
Stoml3
stomatin (Epb7.2)-like 3
MGI:2388072
Synonyms
SLP3, SRO
Feature Type
protein coding gene
Genetic Map
Chromosome 3
25.21 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr3:53488653-53508502 bp, + strand
From VEGA annotation of GRCm38

  19850 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:16628  Vertebrate Homology Class
1 human; 1 mouse; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: STOML3
Gene Tree: Stoml3

Human
homologs
STOML3, stomatin (EPB72)-like 3
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 161003
neXtProt AC: NX_Q8TAV4

Human Synonyms: Epb7.2l, SRO

Human Chr (Location): 13q13.3; chr13:38965925-38990859 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(6) : Gene trapped(1) Targeted(5)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a knock-out allele display loss of mechanoreceptor function and impaired tactile-driven behaviors.
 
Interactions
Stoml3 interacts with 131 markers (Mir7-2, Mir7b, Mir10a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (9 annotations)
Process signal transduction
Component cilium, integral component of membrane, ...
Function protein binding
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (21)    Tissues (15)    Tissue x Stage Matrix (view)
Assay TypeResults
Immunohistochemistry 4
RNA in situ 8
Northern blot 9
cDNA source data(15)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase stoml3 ; ZFIN stoml3b    NEW 
Molecular
reagents
All nucleic(15) cDNA(15)
Microarray probesets(2)
Other database
links
VEGA Gene Model OTTMUSG00000026678 (Evidence)
Ensembl Gene Model ENSMUSG00000027744 (Evidence)
Entrez Gene 229277 (Evidence)
UniGene 222810
DFCI TC1598421
DoTS DT.101362805
NIA Mouse Gene Index U042425
Consensus CDS Project CCDS17347.1
International Mouse Phenotyping Consortium Status Stoml3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000026678 VEGA Gene Model | MGI Sequence Detail 19850 C57BL/6J ±  kb
transcript OTTMUST00000066012 VEGA | MGI Sequence Detail 1780 Not Applicable 
polypeptide OTTMUSP00000032988 VEGA | MGI Sequence Detail 287 Not Applicable 

For the selected sequences
All sequences(27) RefSeq(2) UniProt(2)
Polymorphisms
SNPs within 2kb(238 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001107 Band 7 protein
InterPro IPR018080 Band 7/stomatin-like, conserved site
InterPro IPR001972 Stomatin family
InterPro IPR028519 Stomatin-like protein 3
Protein Ontology PR:000015766 stomatin-like protein 3
References
(Earliest) J:78798 Kobayakawa K, et al., Stomatin-related olfactory protein, SRO, specifically expressed in the murine olfactory sensory neurons. J Neurosci. 2002 Jul 15;22(14):5931-7
(Latest) J:213170 Poole K, et al., Tuning Piezo ion channels to detect molecular-scale movements relevant for fine touch. Nat Commun. 2014;5:3520
All references(32)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory