Stoml3
Gene Detail

Symbol Name ID

Stoml3 stomatin (Epb7.2)-like 3 MGI:2388072

Synonyms

SLP3, SRO

Feature Type

protein coding gene

Genetic Map

Chromosome 3

25.21 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr3:53488727-53508502 bp, + strand From VEGA annotation of GRCm38   19776 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:16628  Vertebrate Homology Class
1 human; 1 mouse; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Stoml3

Human homologs

Human Homolog		STOML3, stomatin (EPB72)-like 3
NCBI Gene ID		161003
neXtProt AC		NX_Q8TAV4
Human Synonyms		Epb7.2l, SRO
Human Chr (Location)		13q13.3; chr13:39540062-39564996 (-)  GRCh37.p10

Alleles and phenotypes

All alleles(6) : Targeted(5) Gene trapped(1)
 

Mice homozygous for a knock-out allele display loss of mechanoreceptor function and impaired tactile-driven behaviors.

 

Gene Ontology (GO) classifications

All GO classifications: (8 annotations)

Process	signal transduction
Component	cilium, integral to membrane, ...
Function	protein binding

External Resources: FuncBase

Expression

Literature Summary: (2 records)
Data Summary: Results (21)    Tissues (14)   
Theiler Stages: 23, 25, 28

Assay Type	Results
Immunohistochemistry	4
RNA in situ	8
Northern blot	9

cDNA source data(15)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(15) cDNA(15)
Microarray probesets(2)

Other database links

VEGA Gene Model	OTTMUSG00000026678 (Evidence)
Ensembl Gene Model	ENSMUSG00000027744 (Evidence)
Entrez Gene	229277 (Evidence)
UniGene	222810
DFCI	TC1598421
DoTS	DT.101362805
NIA Mouse Gene Index	U042425
Consensus CDS Project	CCDS17347.1
International Mouse Knockout Project Status	Stoml3

Sequences

Length	Strain/Species
genomic	OTTMUSG00000026678	VEGA Gene Model | MGI Sequence Detail	19776	C57BL/6J
transcript	OTTMUST00000066012	VEGA | MGI Sequence Detail	1780	Not Applicable
polypeptide	OTTMUSP00000032988	VEGA | MGI Sequence Detail	287	Not Applicable

All sequences(27) RefSeq(2) UniProt(2)

Polymorphisms

SNPs(202 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR001107	Band 7 protein
InterPro	IPR018080	Band 7/stomatin-like, conserved site
InterPro	IPR001972	Stomatin
Protein Ontology	PR:000015766	stomatin-like protein 3

References

(Earliest) J:78798 Kobayakawa K, et al., Stomatin-related olfactory protein, SRO, specifically expressed in the murine olfactory sensory neurons. J Neurosci. 2002 Jul 15;22(14):5931-7
(Latest) J:191236 Wang SZ, et al., Transcription factor ATF5 is required for terminal differentiation and survival of olfactory sensory neurons. Proc Natl Acad Sci U S A. 2012 Nov 6;109(45):18589-94
All references(31)