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Liph
Gene Detail
 Symbol
Name
ID
Liph
lipase, member H
MGI:2388029
Synonyms C130037N08Rik, D16Wsu119e, Lpdlr, LPDLR, mPA-PLA1, PLA1B
Feature Type protein coding gene
Genetic Map
Chromosome 16
12.95 cM, cytoband B1
Detailed Genetic Map ± 1 cM


Mapping data(8)
Sequence Map
Chr16:21953826-21995542 bp, - strand
From Ensembl annotation of GRCm38

  41717 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:71802  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 2 zebrafish

Protein SuperFamily: lipoprotein lipase, LIPH type
Gene Tree: Liph

Human
homologs
Human Homolog LIPH, lipase, member H
NCBI Gene ID 200879
neXtProt AC  NX_Q8WWY8
Human Synonyms  AH, ARWH2, LAH2, LPDLR, mPA-PLA1, PLA1B
Human Chr (Location)  3q27; chr3:185507782-185552588 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human LIPH
Mutations,
alleles, and
phenotypes
All mutations/alleles(15) : Gene trapped(13) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a knock-out allele exhibit wavy vibrissae and wavy and matted coats associated with impaired inner rooth sheath formation.
 
Interactions
Liph interacts with 310 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (30 annotations)
Process lipid catabolic process, lipid metabolic process
Component extracellular region, extracellular space, ...
Function 1-oxa-2-oxocycloheptane lactonase activity, 3,4-dihydrocoumarin hydrolase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (4 records)
Data Summary: Results (103)    Tissues (16)    Images (40)
Theiler Stages: 11, 23
Assay TypeResults
RNA in situ 97
RT-PCR 6
cDNA source data(38)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(49) Genomic(6) cDNA(38) Primer pair(1) Other(4)
Microarray probesets(4)
Other database
links
Ensembl Gene ModelENSMUSG00000044626 (Evidence)
Entrez Gene239759 (Evidence)
UniGene33192
DFCITC1583730, TC1590154, TC1598904, TC1642311, TC1657737, TC1678678
DoTSDT.101332126, DT.521528, DT.91565487
NIA Mouse Gene IndexU036908
EC3.1.1.-
Consensus CDS ProjectCCDS37295.1, CCDS37296.1
International Mouse Knockout Project StatusLiph
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000044626 Ensembl Gene Model | MGI Sequence Detail 41717 C57BL/6J ±  kb
transcript ENSMUST00000060673 Ensembl | MGI Sequence Detail 3793 Not Applicable 
polypeptide ENSMUSP00000062310 Ensembl | MGI Sequence Detail 451 Not Applicable 

For the selected sequences
All sequences(42) RefSeq(8) UniProt(1)
Polymorphisms RFLP(2) : SNPs within 2kb(155 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000734 Lipase
InterPro IPR013818 Lipase, N-terminal
InterPro IPR016272 Lipoprotein lipase, LIPH
Protein Ontology PR:000009837 lipase member H
References (Earliest) J:37738 Kalcheva I, et al., The gene encoding beta-galactoside alpha2,6-sialyltransferase maps to mouse chromosome 16. Mamm Genome. 1997 Aug;8(8):619-20
(Latest) J:196844 Furuta D, et al., Lysophosphatidic acid induces neurite branch formation through LPA3. Mol Cell Neurosci. 2012 May;50(1):21-34
All references(44)
Other
accession IDs
MGD-MRK-35700, MGI:107235, MGI:1206038, MGI:1206041, MGI:2444423

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/23/2014
MGI 5.19
The Jackson Laboratory