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Nek9 Gene Detail
Summary
  • Symbol
    Nek9
  • Name
    NIMA (never in mitosis gene a)-related expressed kinase 9
  • Synonyms
    C130021H08Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2387995
    NCBI Gene: 217718
  • Gene Overview
    MyGene.info: NEK9
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:85299514-85339362 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 12, 39.63 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    154 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2387995
protein coding gene Chr12:85299514-85339362 (-)
129S1/SvImJ MGP_129S1SvImJ_G0019959
protein coding gene Chr12:86069655-86112161 (-)
A/J MGP_AJ_G0019916
protein coding gene Chr12:82802487-82842911 (-)
AKR/J MGP_AKRJ_G0019892
protein coding gene Chr12:85048585-85090740 (-)
BALB/cJ MGP_BALBcJ_G0019896
protein coding gene Chr12:83146323-83186607 (-)
C3H/HeJ MGP_C3HHeJ_G0019702
protein coding gene Chr12:85519319-85561656 (-)
C57BL/6NJ MGP_C57BL6NJ_G0020347
protein coding gene Chr12:88556190-88600819 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017965
protein coding gene Chr12:79689433-79730577 (-)
CAST/EiJ MGP_CASTEiJ_G0019251
protein coding gene Chr12:80490682-80532383 (-)
CBA/J MGP_CBAJ_G0019673
protein coding gene Chr12:91931731-91976582 (-)
DBA/2J MGP_DBA2J_G0019788
protein coding gene Chr12:82318906-82359689 (-)
FVB/NJ MGP_FVBNJ_G0019774
protein coding gene Chr12:81281911-81323025 (-)
LP/J MGP_LPJ_G0019860
protein coding gene Chr12:85945029-85985995 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0019813
protein coding gene Chr12:94810018-94852037 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0020381
protein coding gene Chr12:84651455-84695765 (-)
PWK/PhJ MGP_PWKPhJ_G0019015
protein coding gene Chr12:76821309-76862761 (-)
SPRET/EiJ MGP_SPRETEiJ_G0018810
protein coding gene Chr12:79130211-79175246 (-)
WSB/EiJ MGP_WSBEiJ_G0019303
protein coding gene Chr12:85377852-85423499 (-)



Homology
more
  • Human Ortholog
    NEK9, NIMA related kinase 9
  • Vertebrate Orthologs
    10
  • Human Ortholog
    NEK9, NIMA related kinase 9
    Orthology source: HomoloGene, HGNC
  • Synonyms
    APUG, LCCS10, NC, NERCC, NERCC1
  • Links
    NCBI Gene ID: 91754
    neXtProt AC: NX_Q8TD19
    UniProt: Q8TD19

  • Chr Location
    14q24.3; chr14:75082115-75127075 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 13222
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: NEK9
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    5 phenotypes from 1 allele in 1 genetic background
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 217718 NCBI Gene Model | MGI Sequence Detail 39849 C57BL/6J ±  kb
transcript NM_145138 RefSeq | MGI Sequence Detail 5403 C57BL/6  
polypeptide Q8K1R7 UniProt | EBI | MGI Sequence Detail 984 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 132
    cDNA 131
    Primer pair 1

    Microarray probesets 4
Other
Accession IDs
less
MGI:2442375
References
more
  • Summaries
    All 33
    Gene Ontology 3
    Phenotypes 11
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:261316 Perez-Garcia V, et al., Placentation defects are highly prevalent in embryonic lethal mouse mutants. Nature. 2018 Mar 22;555(7697):463-468

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory